| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4324815 | A | Substrate activity at recombinant mouse SSAT assessed as Vmax at 2000 to 6000 uM | Mus musculus | 2 | ALA4321859 | single protein format | Scientific Literature | |
| 2. | ALA4324816 | A | Substrate activity at recombinant mouse SSAT assessed as Km at 2000 to 6000 uM | Mus musculus | 2 | ALA4321859 | single protein format | Scientific Literature | |
| 3. | ALA4324817 | A | Drug uptake in human DU145 cells assessed as reduction in [14C]-spermine uptake at 1 to 100 uM by competition based assay | Homo sapiens | 4 | ALA4321859 | cell-based format | Scientific Literature | |
| 4. | ALA4324818 | F | Downregulation of intracellular putrescine level in human DU145 Cells assessed per ug DNA at 100 uM after 6 hrs by HPLC method (Rvb = 40 +/- 2 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 5. | ALA4324819 | F | Downregulation of intracellular putrescine level in human DU145 Cells assessed per ug DNA at 100 uM after 3 days by HPLC method (Rvb = 19 +/- 2 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 6. | ALA4324820 | F | Downregulation of intracellular putrescine level in human DU145 Cells assessed per ug DNA at 100 uM in presence of SSAO inhibitor aminoguanidine after 3 days by HPLC method (Rvb = 16 +/- 3 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 7. | ALA4324821 | F | Downregulation of intracellular spermidine level in human DU145 Cells assessed per ug DNA at 100 uM after 6 hrs by HPLC method (Rvb = 134 +/- 7 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 8. | ALA4324822 | F | Downregulation of intracellular spermidine level in human DU145 Cells assessed per ug DNA at 100 uM after 3 days by HPLC method (Rvb = 123 +/- 3 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 9. | ALA4324823 | F | Downregulation of intracellular spermidine level in human DU145 Cells assessed per ug DNA at 100 uM after 3 days in presence of SSAO inhibitor aminoguanidine by HPLC method (Rvb = 175 +/- 5 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 10. | ALA4324824 | F | Downregulation of intracellular spermine level in human DU145 Cells at 100 uM after 6 hrs by HPLC method (Rvb = 106 +/- 4 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 11. | ALA4324825 | F | Downregulation of intracellular spermine level in human DU145 Cells at 100 uM after 3 days by HPLC method (Rvb = 102 +/- 4 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 12. | ALA4324826 | F | Downregulation of intracellular spermine level in human DU145 Cells assessed per ug DNA at 100 uM after 3 days in presence of SSAO inhibitor aminoguanidine by HPLC method (Rvb = 157 +/- 8 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 13. | ALA4324827 | F | Downregulation of intracellular N1-acetylspermidine level in human DU145 cells assessed per ug DNA at 100 uM after 6 hrs by HPLC method (Rvb < 3 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 14. | ALA4324828 | F | Downregulation of intracellular N1-acetylspermidine level in human DU145 cells assessed per ug DNA at 100 uM after 3 days by HPLC method (Rvb = 3 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 15. | ALA4324829 | F | Downregulation of intracellular N1-acetylspermidine level in human DU145 cells assessed per ug DNA at 100 uM after 3 days in presence of SSAO inhibitor aminoguanidine by HPLC method (Rvb = 3 +/- 1 pmol/ug) | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 16. | ALA4324830 | A | Substrate activity at OAZ1 in human DU145 cells assessed as enzyme-mediated drug uptake at 100 uM in presence of CHX after 4 hrs by HPLC method | Homo sapiens | 4 | ALA4321859 | cell-based format | Scientific Literature | |
| 17. | ALA4324831 | A | Drug level in human DU145 cells assessed per ug DNA at 100 uM after 6 hrs by HPLC method | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 18. | ALA4324832 | A | Drug level in human DU145 cells assessed per ug DNA at 100 uM after 3 days by HPLC method | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 19. | ALA4324833 | A | Drug level in human DU145 cells at 100 uM in presence of SSAO inhibitor aminoguanidine after 3 days by HPLC method | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature | |
| 20. | ALA4324834 | A | Drug metabolism in human DU145 cells at 100 uM assessed as methylspermidine metabolite level assessed per ug DNA after 6 hrs by HPLC method | Homo sapiens | 3 | ALA4321859 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!