| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4305082 | A | Antiproliferative activity in mouse BAF3 cells after 72 hrs by CCK8 assay | Mus musculus | 31 | ALA4304743 | cell-based format | Scientific Literature | |
| 2. | ALA4305083 | A | Inhibition of wild type TEL fused c-KIT (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 32 | ALA4304743 | cell-based format | Scientific Literature | |
| 3. | ALA4305084 | B | Inhibition of TEL fused c-KIT T670I mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 32 | ALA4304743 | cell-based format | Scientific Literature | |
| 4. | ALA4305085 | U | Selectivity ratio, ratio of inhibition of wild type TEL fused c-KIT (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition to inhibition of TEL fused c-KIT T670I mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition | Homo sapiens | 6 | ALA4304743 | cell-based format | Scientific Literature | |
| 5. | ALA4305086 | B | Inhibition of TEL fused c-KIT V559D mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 6. | ALA4305087 | B | Inhibition of TEL fused c-KIT V559A mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 7. | ALA4305088 | B | Inhibition of TEL fused c-KIT V559G mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 8. | ALA4305089 | B | Inhibition of TEL fused c-KIT L576P mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 9. | ALA4305090 | B | Inhibition of TEL fused c-KIT V654A/V559D double mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 10. | ALA4305091 | B | Inhibition of TEL fused c-KIT V654A mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 11. | ALA4305092 | B | Inhibition of TEL fused c-KIT T670I/V559D double mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 12. | ALA4305093 | B | Inhibition of TEL fused c-KIT D816V mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 13. | ALA4305094 | B | Inhibition of TEL fused c-KIT D816H mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 14. | ALA4305095 | B | Inhibition of TEL fused c-KIT D820E mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 15. | ALA4305096 | B | Inhibition of TEL fused c-KIT N822K mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 16. | ALA4305097 | B | Inhibition of TEL fused c-KIT A829P mutant (unknown origin) transfected in mouse BAF3 cells assessed as growth inhibition after 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA4304743 | cell-based format | Scientific Literature | |
| 17. | ALA4305100 | A | Inhibition of wild-type His-tagged c-KIT (unknown origin) expressed in baculovirus infected sf9 cells pre-incubated for 60 mins followed by ATP addition and measured after 1 hr by Z-LYTE assay | Homo sapiens | 1 | ALA4304743 | cell-based format | Scientific Literature | |
| 18. | ALA4305101 | B | Inhibition of His-tagged c-KIT T670I mutant (544 to 935 residues) (unknown origin) expressed in baculovirus infected sf9 cells pre-incubated for 60 mins followed by ATP addition and measured after 1 hr by Z-LYTE assay | Homo sapiens | 1 | ALA4304743 | cell-based format | Scientific Literature | |
| 19. | ALA4305102 | A | Inhibition of TEL fused wild type c-KIT (unknown origin) transfected in mouse BaF3 cells assessed as reduction in phosphorylation at Y703 residue after 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA4304743 | cell-based format | Scientific Literature | |
| 20. | ALA4305103 | B | Selectivity ratio, ratio of IC50 for wild-type His-tagged c-KIT (unknown origin) expressed in baculovirus infected sf9 cells to IC50 for His-tagged c-KIT T670I mutant (544 to 935 residues) (unknown origin) expressed in baculovirus infected sf9 cells | Homo sapiens | 1 | ALA4304743 | cell-based format | Scientific Literature |
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