| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4327508 | B | Inhibition of human FMS assessed as residual activity at 1 uM using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA4327509 | B | Inhibition of human FLT4 assessed as residual activity at 1 uM using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA4327510 | B | Inhibition of human CDK2/cyclin-A1 assessed as residual activity at 1 uM using histone H1 as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 4. | ALA4327511 | B | Inhibition of human FLT3 assessed as residual activity at 1 uM using EAIYAAPFAKKK as substrate by [gamma-33P]-ATP assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA4327512 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4327513 | F | Potentiation of 5-fluorouracil-induced cytotoxicity against human HCT116 cells assessed as 5-fluorouracil IC50 at 0.5 uM by MTT assay (Rvb = 15.16 +/- 4.2 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4327514 | F | Potentiation of 5-fluorouracil-induced cytotoxicity against human HCT116 cells assessed as 5-fluorouracil IC50 at 1 uM by MTT assay (Rvb = 15.16 +/- 4.2 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4327515 | F | Potentiation of 5-fluorouracil-induced cytotoxicity against human HT-29 cells assessed as 5-fluorouracil IC50 at 0.5 uM by MTT assay (Rvb = 16.45 +/- 2.627 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4327516 | F | Potentiation of 5-fluorouracil-induced cytotoxicity against human HT-29 cells assessed as 5-fluorouracil IC50 at 1 uM by MTT assay (Rvb = 16.45 +/- 2.627 uM) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4327517 | F | Cytotoxicity against human FOLFOX-resistant HCT116 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4327518 | F | Cytotoxicity against human FOLFOX-resistant HT-29 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4327519 | F | Inhibition of spheroid formation in human CA2 cells after 7 days by microscopic method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4327520 | F | Potentiation of 5-fluorouracil-induced cell cycle arrest in human HCT116 cells assessed as accumulation at S phase at 20 uM treated for 8 hrs starting from 24 hrs post 5-fluorouracil addition by FACS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4327521 | F | Potentiation of 5-fluorouracil-induced cell cycle arrest in human HCT116 cells assessed as accumulation at G2/M phase at 20 uM treated for 8 hrs starting from 24 hrs post 5-fluorouracil addition by FACS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4327523 | B | Inhibition of hydroxyurea-induced CHK1 phosphorylation at S317 residue in human HCT116 cells at 20 uM treated for 8 hrs starting from 24 hrs post hydroxyurea addition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4327524 | B | Inhibition of hydroxyurea-induced CHK1 phosphorylation at S345 residue in human HCT116 cells at 20 uM treated for 8 hrs starting from 24 hrs post hydroxyurea addition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4327525 | B | Inhibition of hydroxyurea-induced CHK1 phosphorylation at S296 residue in human HCT116 cells at 20 uM treated for 8 hrs starting from 24 hrs post hydroxyurea addition by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4327526 | B | Inhibition of CHK1 phosphorylation at S317 residue in human HCT116 cells at 20 uM after 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4327527 | B | Inhibition of CHK1 phosphorylation at S345 residue in human HCT116 cells at 20 uM after 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4327528 | B | Inhibition of CHK1 phosphorylation at S296 residue in human HCT116 cells at 20 uM after 8 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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