| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4415677 | A | Cytotoxicity against human MRC5 SV2 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 2. | ALA4415678 | F | Antitrypanosomal activity against Trypanosoma cruzi Tulahuen CL2 amastigotes infected in human MRC5 SV2 cells incubated for 7 days by chlorophenol red beta-D-galactopyranoside substrate based spectrophotometric assay | Trypanosoma cruzi | 29 | organism-based format | Scientific Literature | ||
| 3. | ALA4415679 | T | Selectivity index, ratio for EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 amastigotes infected in human MRC5 SV2 cells | 16 | cell-based format | Scientific Literature | |||
| 4. | ALA4415680 | A | Drug metabolism in mouse liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM measured immediately in presence of NADPH by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 5. | ALA4415681 | A | Drug metabolism in mouse liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 15 mins in presence of NADPH by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 6. | ALA4415682 | A | Drug metabolism in mouse liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 30 mins in presence of NADPH by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 7. | ALA4415683 | A | Drug metabolism in mouse liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 60 mins in presence of NADPH by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 8. | ALA4415684 | A | Drug metabolism in mouse liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM measured immediately in presence of UDPGA by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 9. | ALA4415685 | A | Drug metabolism in mouse liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 15 mins in presence of UDPGA by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 10. | ALA4415686 | A | Drug metabolism in mouse liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 30 mins in presence of UDPGA by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 11. | ALA4415687 | A | Drug metabolism in mouse liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 60 mins in presence of UDPGA by UPLC-MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 12. | ALA4415688 | A | Drug metabolism in rat liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM measured immediately in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 13. | ALA4415689 | A | Drug metabolism in rat liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 15 mins in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 14. | ALA4415690 | A | Drug metabolism in rat liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 30 mins in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 15. | ALA4415691 | A | Drug metabolism in rat liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM incubated for 60 mins in presence of NADPH by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 16. | ALA4415692 | A | Drug metabolism in rat liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM measured immediately in presence of UDPGA by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 17. | ALA4415693 | A | Drug metabolism in rat liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 15 mins in presence of UDPGA by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 18. | ALA4415694 | A | Drug metabolism in rat liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 30 mins in presence of UDPGA by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 19. | ALA4415695 | A | Drug metabolism in rat liver microsomes assessed as UGT-mediated metabolism by measuring compound remaining at 5 uM incubated for 60 mins in presence of UDPGA by UPLC-MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 20. | ALA4415696 | A | Drug metabolism in dog liver microsomes assessed as CYP450-mediated metabolism by measuring parent compound remaining at 5 uM measured immediately in presence of NADPH by UPLC-MS analysis | Canis lupus familiaris | 1 | microsome format | Scientific Literature |
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