# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4368093 | B | Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interval for 20 mins by fluorometic method | Homo sapiens | 22 | ALA4364319 | cell-based format | Scientific Literature | |
2. | ALA4368094 | A | Inhibition of DPP8 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interval for 20 mins by fluorometic method | Homo sapiens | 23 | ALA4364319 | single protein format | Scientific Literature | |
3. | ALA4368095 | A | Inhibition of DPP9 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition measured at 60 secs interval for 20 mins by fluorometic method | Homo sapiens | 23 | ALA4364319 | single protein format | Scientific Literature | |
4. | ALA4413684 | B | Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells at 200 nM using Gly-Pro-AMC as substrate measured at 60 secs interval for 20 mins by fluorescence assay relative to control | Homo sapiens | 24 | ALA4411317 | cell-based format | Scientific Literature | |
5. | ALA4413685 | B | Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells at 40 nM using Gly-Pro-AMC as substrate measured at 60 secs interval for 20 mins by fluorescence assay relative to control | Homo sapiens | 24 | ALA4411317 | cell-based format | Scientific Literature | |
6. | ALA4413686 | B | Inhibition of recombinant human DPP4 expressed in baculovirus infected Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 secs interval for 20 mins by fluorescence assay | Homo sapiens | 24 | ALA4411317 | cell-based format | Scientific Literature | |
7. | ALA4413687 | A | Inhibition of recombinant full-length human N-terminal GST-tagged DPP8 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 secs interval for 20 mins by fluorescence assay | Homo sapiens | 12 | ALA4411317 | cell-based format | Scientific Literature | |
8. | ALA4413688 | A | Inhibition of recombinant full-length human N-terminal GST-tagged DPP9 expressed in Sf9 insect cells using Gly-Pro-AMC as substrate measured at 60 secs interval for 20 mins by fluorescence assay | Homo sapiens | 12 | ALA4411317 | cell-based format | Scientific Literature | |
9. | ALA4413689 | A | Cytotoxicity against human LO2 cells assessed as cell viability at 100 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 4 | ALA4411317 | cell-based format | Scientific Literature | |
10. | ALA4413690 | A | Cytotoxicity against human LO2 cells assessed as cell viability at 50 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 3 | ALA4411317 | cell-based format | Scientific Literature | |
11. | ALA4413692 | F | Hypoglycemic activity in Kunming mouse assessed as decrease in blood glucose AUC (0 to 120 mins) at 10 mg/kg, po administered as single dose treated for 30 mins prior to glucose load by OGTT relative to control | Mus musculus | 3 | ALA4411317 | organism-based format | Scientific Literature | |
12. | ALA4413693 | P | Retention time of the compound in water at 1 uM by LC/MS/MS method | 2 | ALA4411317 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4413696 | A | Retention time of the compound in rat plasma by LC/MS/MS method | Rattus norvegicus | 1 | ALA4411317 | cell-free format | Scientific Literature | |
14. | ALA5247222 | B | Inhibition of human recombinant DPP-4 | Homo sapiens | 9 | ALA5244277 | single protein format | Scientific Literature | |
15. | ALA5247223 | B | Inhibition of human recombinant DPP-8 | Homo sapiens | 2 | ALA5244277 | single protein format | Scientific Literature | |
16. | ALA5247224 | B | Inhibition of human recombinant DPP-9 | Homo sapiens | 2 | ALA5244277 | single protein format | Scientific Literature |