| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4380816 | B | Inhibition of recombinant human C-terminal GST-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in SMRT/BTB domain interaction incubated for 1 hr by HTRF assay | Homo sapiens | 32 | ALA4376875 | cell-based format | Scientific Literature | |
| 2. | ALA4380817 | B | Potency index, ratio of IC50 of 3-[5-(5-chloro-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl]propanoic acid to IC50 of compound for inhibition of recombinant human C-terminal GST-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in SMRT/BTB domain interaction incubated for 1 hr by HTRF assay | Homo sapiens | 2 | ALA4376875 | cell-based format | Scientific Literature | |
| 3. | ALA4380819 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of ATR mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | ALA4376875 | cell-based format | Scientific Literature | |
| 4. | ALA4380820 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of CXCR4 mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | ALA4376875 | cell-based format | Scientific Literature | |
| 5. | ALA4380821 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of CD69 mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | ALA4376875 | cell-based format | Scientific Literature | |
| 6. | ALA5223604 | B | Inhibition of BCL6/SMRT protein protein interaction (unknown origin) by TR-FRET assay | Homo sapiens | 3 | ALA5223079 | protein format | Scientific Literature |
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