# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4410383 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) pdm09 infected in MDCK cells assessed as inhibition of virus replication compound incubated with uninfected host cell for 1 hr followed by viral infection for 24 hrs measured after viral cultivation in host cell for 48 hrs by hemagglutination test | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 20 | ALA4406883 | organism-based format | Scientific Literature | |
2. | ALA4410384 | A | Cytotoxicity against dog MDCK cells assessed as cell death incubated for 48 hrs by MTT assay | Canis lupus familiaris | 20 | ALA4406883 | cell-based format | Scientific Literature | |
3. | ALA4410385 | T | Selectivity index, ratio of CTD50 for dog MDCK cells to IC50 for Influenza A virus (A/Puerto Rico/8/34 (H1N1)) pdm09 infected in MDCK cells | 20 | ALA4406883 | cell-based format | Scientific Literature | ||
4. | ALA4410386 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) pdm09 infected in MDCK cells assessed as reduction in infectious viral titer at 300 umol/lL treated with compound at 0 to 2 hrs post-infection measured after cultivation of virus in host cell for 8 hrs by hemagglutination test | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4406883 | organism-based format | Scientific Literature | |
5. | ALA4410387 | F | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) pdm09 infected in MDCK cells assessed as infectious viral titer at 300 umol/lL treated with compound at 4 to 8 hrs post-infection measured after cultivation of virus in host cell for 8 hrs by hemagglutination test | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | 1 | ALA4406883 | organism-based format | Scientific Literature |