| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4386596 | B | Inhibition of recombinant wild type full length His-tagged HCV genotype 1b NS3 (1027 to 1657 residues)/4A (1658 to 1711 residues) protease expressed in Escherichia coli rosetta (DE3) cells using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus subtype 1b | 12 | ALA4385618 | cell-based format | Scientific Literature | |
| 2. | ALA4386597 | B | Inhibition of recombinant full length His-tagged HCV genotype 1b NS3/4A (1027 to 1657 residues) protease R155K (NS3) mutant expressed in Escherichia coli rosetta (DE3) cells using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus subtype 1b | 4 | ALA4385618 | cell-based format | Scientific Literature | |
| 3. | ALA4386599 | B | Inhibition of recombinant HCV genotype 4 NS3/4A protease using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus genotype 4 | 4 | ALA4385618 | assay format | Scientific Literature | |
| 4. | ALA4386600 | B | Inhibition of recombinant HCV genotype 3a NS3/4A protease using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus subtype 3a | 5 | ALA4385618 | assay format | Scientific Literature | |
| 5. | ALA4386601 | B | Inhibition of recombinant HCV genotype 2a NS3/4A protease using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus subtype 2a | 4 | ALA4385618 | assay format | Scientific Literature | |
| 6. | ALA4386603 | B | Inhibition of recombinant HCV genotype 1a NS3/4A protease using Ac-DE-Dap(QXL520)-EE-Abu-Psi-[COO]AS-C(5-FAMsp)-NH2 as substrate preincubated up to 10 mins followed by substrate addition and measured for 10 mins by fluorescence-based microplate reader analysis | Hepatitis C virus subtype 1a | 4 | ALA4385618 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!