# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4354172 | B | Inhibition of Con A-induced NF-kappaB p65 translocation in mouse RAW264.7 cells incubated for 22 hrs by DAPI staining based laser scanning confocal microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
2. | ALA4354173 | F | Inhibition of MCP-1 mediated chemotaxis in mouse RAW264.7 cells at 20 uM measured after 3 hrs by light microscopic analysis relative to control | Mus musculus | 4 | cell-based format | Scientific Literature | ||
3. | ALA4354174 | F | Antiinflammatory activity in mouse RAW264.7 cells assessed as LPS-induced nitric oxide level at 20 uM preincubated for 1 hr followed by LPS treatment and measured after 23 hrs by Griess reagent based assay (Rvb = 96.06 to 102.81%) | Mus musculus | 35 | cell-based format | Scientific Literature | ||
4. | ALA4354175 | B | Inhibition of LPS-induced NF-kappaB p65 translocation in mouse RAW264.7 cells incubated for 22 hrs by DAPI staining based laser scanning confocal microscopic analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4354176 | F | Antiinflammatory activity against mouse RAW264.7 assessed as decrease in Con-A induced TNF-alpha mRNA expression level at 1 uM measured after 22 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA4354177 | F | Antiinflammatory activity against mouse RAW264.7 assessed as decrease in Con-A induced INF-gamma mRNA expression level at 1 uM measured after 22 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4354178 | F | Antiinflammatory activity against mouse RAW264.7 assessed as decrease in Con-A induced IL-6 mRNA expression level at 1 uM measured after 22 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4354179 | F | Antiinflammatory activity against mouse RAW264.7 assessed as decrease in Con-A induced TNF-alpha IL-10 expression level at 1 uM measured after 22 hrs by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA4354180 | A | Cytotoxicity against human LO2 cells assessed as cell viability at 20 uM measured after 24 hrs by MTT assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
10. | ALA4354181 | F | Antiinflammatory activity in mouse model of Con-A induced autoimmune hepatitis assessed as decrease in serum ALT level at 100 mg/kg, ip measured after 12 hrs relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA4354182 | F | Antiinflammatory activity in mouse model of Con-A induced autoimmune hepatitis assessed as decrease in serum AST level at 100 mg/kg, ip measured after 12 hrs relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA4354183 | F | Hepatoprotective activity in mouse model of Con-A induced autoimmune hepatitis assessed as reduction in Con-A induced CD4-positive cells infiltration by H and E staining based microscopic analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA4354184 | F | Hepatoprotective activity in mouse model of Con-A induced autoimmune hepatitis assessed as decrease in necrosis of hepatocytes by H and E staining based fluorescence microscopic analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
14. | ALA4354185 | F | Hepatoprotective activity in mouse model of Con-A induced autoimmune hepatitis assessed as reduction in Con-A induced F4/80-positive cells infiltration by H and E staining based microscopic analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
15. | ALA4354186 | F | Hepatoprotective activity in mouse model of Con-A induced autoimmune hepatitis assessed as reduction in Con-A induced CD11b-positive cells infiltration by H and E staining based microscopic analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
16. | ALA4354187 | F | Antiinflammatory activity in mouse model of Con-A induced autoimmune hepatitis assessed as of MDSC accumulation at 100 mg/kg by flow cytometry analysis (Rvb = 11.31%) | Mus musculus | 1 | organism-based format | Scientific Literature |