| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5139556 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as inhibition of bacterial growth | Mycobacterium tuberculosis | 37 | organism-based format | Scientific Literature | ||
| 2. | ALA5139575 | F | Antibacterial activity against Mycobacterium tuberculosis in acute Mtb infection BALB/c mouse model assessed as reduction in log10 CFU in lungs at 100 mg/kg for 3 weeks | Mycobacterium tuberculosis | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA5139587 | B | Inhibition of N-terminal thioredoxin-tagged Mycobacterium smegmatis DprE1 expressed in Escherichia coli BL21(DE3) incubated for 7 days by microplate alamar blue assay | Mycolicibacterium smegmatis | 1 | assay format | Scientific Literature | ||
| 4. | ALA5139588 | F | Cytotoxicity against human HepG2 cells treated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5139589 | T | Cytotoxicity against African green monkey Vero cells treated for 72 hrs by MTT assay | Chlorocebus sabaeus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5139590 | F | Antibacterial activity against Mycobacterium tuberculosis in chronic Mtb infection BALB/c mouse model assessed as reduction in log10 CFU in lungs at 200 mg/kg for 4 weeks | Mycobacterium tuberculosis | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA5139591 | A | Inhibition of CYP2C9 (unknown origin) using diclofenac as substrate incubated for 20 to 30 mins by LC-MS/MS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5139593 | T | Inhibition of hERG | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 9. | ALA4371338 | B | Inhibition of N-terminal His6-thioredoxin tagged Mycobacterium tuberculosis H37Rv DprE1 expressed in Escherichia coli BL21(DE3) using FPR as substrate by resazurin dye-based fluorescence assay | Mycobacterium tuberculosis H37Rv | 5 | assay format | Scientific Literature | ||
| 10. | ALA4371339 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 30 mins by in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 11. | ALA5144281 | F | Antimycobacterial activity against Mycobacterium smegmatis wild type DprE1 assessed as inhibition of bacterial growth incubated for 7 days by by microplate alamar blue assay | Mycolicibacterium smegmatis | 3 | organism-based format | Scientific Literature |
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