| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4346930 | B | Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as activation of SEAP incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 2. | ALA4346931 | B | Agonist activity at human TLR1/2 expressed in HEK-Blue cells assessed as activation of SEAP at 0.5 uM incubated for 24 hrs by quanti-blue SEAP assay in presence of Anti-hTLR2-IgA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4346932 | B | Agonist activity at human TLR3 expressed in HEK-Blue cells assessed as activation of SEAP up to 100 uM incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4346933 | B | Agonist activity at human TLR4 expressed in HEK-Blue cells assessed as activation of SEAP up to 100 uM incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4346934 | B | Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as increase in TLR2 expression at 0.1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4346935 | B | Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as increase in TLR2 expression at 10 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4346936 | B | Agonist activity at human TLR1/2 expressed in HEK-Blue cells assessed as activation of SEAP at 0.5 uM incubated for 24 hrs by quanti-blue SEAP assay in presence of Anti-hTLR1-IgG | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4346937 | B | Agonist activity at human TLR2 in PMA differentiated THP-1 cells assessed as TNF-alpha production incubated for 4 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4346938 | B | Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as NF-kappaB activation at 10 uM incubated for 24 hrs in presence of NF-kappaB inhibitor, triptolide by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4346939 | A | Cytotoxicity against human HEK-Blue cells transfected with hTLR2 assessed as cell viability upto 100 uM incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4346941 | B | Agonist activity at human TLR2/6 expressed in HEK-Blue cells assessed as activation of SEAP at 0.5 uM incubated for 24 hrs by quanti-blue SEAP assay in presence of Anti-hTLR6-IgG | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4346942 | B | Agonist activity at human TLR3 expressed in HEK-Blue cells assessed as activation of SEAP at 40 ng/ml incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4346943 | B | Agonist activity at human TLR4 expressed in HEK-Blue cells assessed as activation of SEAP at 10 ug/ml incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4346944 | B | Agonist activity at human TLR2 expressed in HEK-Blue cells assessed as NF-kappaB activation at 10 uM incubated for 24 hrs by quanti-blue SEAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!