| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4401552 | F | Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 22 | ALA4400541 | cell-based format | Scientific Literature | |
| 2. | ALA4401553 | F | Cytotoxicity against human CCRF-CEM/VBL cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 22 | ALA4400541 | cell-based format | Scientific Literature | |
| 3. | ALA4401554 | F | Resistance factor, ratio of IC50 for human CCRF-CEM/VBL cells to IC50 for human CCRF-CEM cells | Homo sapiens | 22 | ALA4400541 | assay format | Scientific Literature | |
| 4. | ALA4401555 | F | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 7 | ALA4400541 | cell-based format | Scientific Literature | |
| 5. | ALA4401556 | F | Cytotoxicity against human H460 cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 7 | ALA4400541 | cell-based format | Scientific Literature | |
| 6. | ALA4401557 | F | Cytotoxicity against human NCI-H526 cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 7 | ALA4400541 | cell-based format | Scientific Literature | |
| 7. | ALA4401558 | B | Induction of pEGFP-N1 DNA (unknown origin) interstrand cross linking after 2 hrs by alkaline gel electrophoresis | Not specified | 1 | ALA4400541 | assay format | Scientific Literature | |
| 8. | ALA4401560 | F | Induction of cell cycle arrest in human NCI-H460 cells assessed as accumulation at G2/M phase at 0.125 to 0.25 uM after 24 to 72 hrs by propidium iodide-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 9. | ALA4401561 | F | Induction of cell cycle arrest in human NCI-H460 cells assessed as accumulation at S phase at 0.5 uM after 24 to 72 hrs by propidium iodide-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 10. | ALA4401562 | F | Induction of cell cycle arrest in human NCI-H460 cells assessed as accumulation at G1 phase at 1 to 2 uM after 24 to 72 hrs by propidium iodide-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 11. | ALA4401563 | F | Induction of cell cycle arrest in human NCI-H460 cells assessed as accumulation at subG1 phase at 0.125 to 2 uM after 24 to 72 hrs by propidium iodide-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 12. | ALA4401564 | F | Induction of apoptosis in human NCI-H460 cells assessed as increase in early apoptotic cells after 48 hrs by Annexin V/FITC-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 13. | ALA4401565 | F | Cytotoxicity against human EAhy926 cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 3 | ALA4400541 | cell-based format | Scientific Literature | |
| 14. | ALA4401566 | F | Induction of apoptosis in human NCI-H460 cells assessed as increase in late apoptotic cells after 48 hrs by Annexin V/FITC-based flow cytometry | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 15. | ALA4401567 | B | Inhibition of VEGFR2 phosphorylation in human NCI-H460 cells after 12 hrs by Western blot analysis | Homo sapiens | 2 | ALA4400541 | cell-based format | Scientific Literature | |
| 16. | ALA4401568 | F | Antimigratory activity against human EAhy926 cells up to 0.5 uM after 12 hrs by transwell assay | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 17. | ALA4401569 | F | Antiangiogenic activity against human EAhy926 cells assessed as reduction in tube formation after 24 hrs by matrigel-based light microscopic analysis | Homo sapiens | 2 | ALA4400541 | cell-based format | Scientific Literature | |
| 18. | ALA4401570 | F | Antiangiogenic activity against human EAhy926 cells assessed as reduction in tube formation after 24 hrs by matrigel-based light microscopic analysis relative to vatalanib | Homo sapiens | 1 | ALA4400541 | cell-based format | Scientific Literature | |
| 19. | ALA4401571 | F | Antitumor activity against human NCI-H526 cells xenografted in iv dosed nu/nu mouse assessed as tumor growth inhibition administered in liposomal formulation for every other day for 6 days | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 20. | ALA4401572 | F | Antitumor activity against human NCI-H526 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, iv administered in liposomal formulation for every other day for 6 days and measured on day 30 post dose relative to control | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature |
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