#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4411915	Binding	Displacement of [3H]-mibolerone from recombinant wild-type GST-tagged androgen receptor LBD (unknown origin) after 16 hrs by scintillation counting analysis	Homo sapiens	40	ALA4411271	single protein format	Scientific Literature
2.	ALA4411916	Binding	Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of R1881-induced receptor transactivation after 24 hrs by luciferase reporter gene assay	Homo sapiens	41	ALA4411271	cell-based format	Scientific Literature
3.	ALA4411917	Binding	Induction of full length androgen receptor degradation in human LNCaP cells at 1 uM after 24 hrs in presence of R1881 by Western blot analysis relative to control	Homo sapiens	41	ALA4411271	cell-based format	Scientific Literature
4.	ALA4411918	Binding	Induction of androgen receptor splice variant mutant degradation in human 22RV1 cells at 10 uM after 24 hrs in presence of R1881 by Western blot analysis relative to control	Homo sapiens	41	ALA4411271	cell-based format	Scientific Literature
5.	ALA4411919	Functional	Antiproliferative activity against human MR49F cells after 3 days followed by compound wash and measured after 6 days by SRB assay	Homo sapiens	35	ALA4411271	cell-based format	Scientific Literature
6.	ALA4411920	Binding	Induction of estrogen receptor degradation in human MCF7 cells up to 10 uM after 24 hrs by Western blot analysis	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature
7.	ALA4411921	Functional	Reduction in androgen receptor protein level in human LNCAP cells at 10 uM after 8 hrs by Western blot analysis	Homo sapiens	1	ALA4411271	cell-based format	Scientific Literature
8.	ALA4411923	Binding	Induction of androgen receptor degradation in human LNCaP cells at 10 uM after 8 hrs in presence of cycloheximide by Western blot analysis	Homo sapiens	1	ALA4411271	cell-based format	Scientific Literature
9.	ALA4411924	ADME	Half life in mouse liver microsomes at 50 uM in presence of cofactors for phase 1 and 2 metabolism	Mus musculus	20	ALA4411271	microsome format	Scientific Literature
10.	ALA4411925	ADME	Intrinsic clearance in mouse liver microsomes at 50 uM in presence of cofactors for phase 1 and 2 metabolism	Mus musculus	20	ALA4411271	microsome format	Scientific Literature
11.	ALA4411930	Binding	Induction of androgen receptor splice F876L/T877A double mutant degradation in human MR49F cells up to 10 uM after 48 hrs by luciferase reporter gene assay	Homo sapiens	3	ALA4411271	cell-based format	Scientific Literature
12.	ALA4411931	Binding	Induction of full length androgen receptor degradation in human LNCaP cells at 0.1 to 10 uM after 24 hrs in presence of R1881 by Western blot analysis relative to control	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature
13.	ALA4411932	Functional	Antiproliferative activity against human MR49F cells after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay	Homo sapiens	3	ALA4411271	cell-based format	Scientific Literature
14.	ALA4411936	ADME	Cytotoxicity against human PC3 cells at 10 uM after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature
15.	ALA4411937	Binding	Induction of full length androgen receptor degradation in human MR49F cells assessed as ratio of androgen receptor expression levels to GAPDH expression levels at 10 uM after 8 hrs in presence of cycloheximide by Western blot analysis	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature
16.	ALA4411938	Binding	Induction of full length androgen receptor degradation in human MR49F cells assessed as ratio of androgen receptor expression levels to GAPDH expression levels at 10 uM after 8 hrs in presence of cycloheximide and proteasome inhibitor bortezomib by Western blot analysis	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature
17.	ALA4411939	Functional	In vivo antagonist activity at androgen receptor in C57B/L6 mouse assessed as induction of seminal vesicles atrophy at 40 mg/kg/day, po for 14 days by Hershberger assay	Mus musculus	9	ALA4411271	organism-based format	Scientific Literature
18.	ALA4411945	Functional	Antitumor activity against human MR49F cells xenografted in NSG cells assessed as tumor growth inhibition at 100 mg/kg/day, po for 14 days and measured twice weekly relative to control	Homo sapiens	2	ALA4411271	organism-based format	Scientific Literature
19.	ALA4411949	Binding	Antagonist activity at rat GR expressed in COS cells assessed as reduction in receptor transactivation incubated for 24 hrs by luciferase reporter gene assay	Rattus norvegicus	4	ALA4411271	cell-based format	Scientific Literature
20.	ALA4411950	Binding	Antagonist activity at ER (unknown origin) expressed in HEK293 cells assessed as reduction in receptor transactivation incubated for 48 hrs by luciferase reporter gene assay	Homo sapiens	2	ALA4411271	cell-based format	Scientific Literature