# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4362630 | F | Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites assessed as reduction in viable cells at 50 ug/ml incubated for 24 hrs by trypan blue staining based hemocytometric method relative to control | Acanthamoeba castellanii | 15 | organism-based format | Scientific Literature | ||
2. | ALA4362631 | F | Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 trophozites assessed as reduction in viable cells at 100 ug/ml incubated for 24 hrs by trypan blue staining based hemocytometric method relative to control | Acanthamoeba castellanii | 14 | organism-based format | Scientific Literature | ||
3. | ALA4362632 | F | Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 assessed as increase in surface disintegration at 100 ug/ml incubated for 2 hrs by FE-SEM analysis | Acanthamoeba castellanii | 2 | organism-based format | Scientific Literature | ||
4. | ALA4362633 | F | Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 assessed as increase in pore formation at 100 ug/ml incubated for 2 hrs by FE-SEM analysis | Acanthamoeba castellanii | 2 | organism-based format | Scientific Literature | ||
5. | ALA4362635 | F | Inhibition of Acanthamoeba castellanii T4 genotype ATCC 50492 excystation at 100 ug/ml incubated with pre-formed cysts for 72 hrs by hemocytometric method | Acanthamoeba castellanii | 16 | organism-based format | Scientific Literature | ||
6. | ALA4362636 | A | Cytotoxicity against human HaCaT cells at 100 ug/ml incubated for 24 hrs by LDH release assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
7. | ALA4362638 | F | Antiamoebic activity against Acanthamoeba castellanii T4 genotype ATCC 50492 infected in human HaCaT cells assessed as reduction in amoeba-induced host cell cytopathogenicity at 100 ug/ml preincubated with amoeba for 2 hrs followed by incubation of suspension with host cell for 24 hrs by LDH release assay relative to control | Acanthamoeba castellanii | 4 | organism-based format | Scientific Literature |