# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4385382 | B | Activity at rat KCNQ2 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Rattus norvegicus | 29 | ALA4382285 | cell-based format | Scientific Literature | |
2. | ALA4385383 | B | Activity at human KCNQ4 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Homo sapiens | 28 | ALA4382285 | cell-based format | Scientific Literature | |
3. | ALA4385384 | B | Activity at human KCNQ5 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Homo sapiens | 28 | ALA4382285 | cell-based format | Scientific Literature | |
4. | ALA4385386 | B | Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
5. | ALA4385387 | B | Activity at rat homomeric KCNQ2 expressed in CHOK1 cells assessed as effect on current amplitude up to 30 uM at -10 mV by whole cell patch clamp assay | Rattus norvegicus | 1 | ALA4382285 | cell-based format | Scientific Literature | |
6. | ALA4385388 | A | Activation of rat homomeric KCNQ2 expressed in CHOK1 cells increase in current amplitude at 30 uM at -10 mV by whole cell patch clamp assay relative to control | Rattus norvegicus | 1 | ALA4382285 | cell-based format | Scientific Literature | |
7. | ALA4385389 | B | Activity at human KCNQ1 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
8. | ALA4385390 | B | Activity at rat KCNQ3 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at -10 mV by whole cell patch clamp assay | Rattus norvegicus | 1 | ALA4382285 | cell-based format | Scientific Literature | |
9. | ALA4385391 | B | Activity at human KCNQ1 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
10. | ALA4385392 | B | Activity at rat KCNQ2 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Rattus norvegicus | 1 | ALA4382285 | cell-based format | Scientific Literature | |
11. | ALA4385393 | B | Activity at rat KCNQ3 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Rattus norvegicus | 1 | ALA4382285 | cell-based format | Scientific Literature | |
12. | ALA4385394 | B | Activity at human KCNQ4 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
13. | ALA4385395 | B | Activity at human KCNQ5 expressed in CHOK1 cells assessed as ratio of amplitude of outward current in presence of test compound to amplitude of outward current in absence of test compound at 10 uM at +60 mV by whole cell patch clamp assay | Homo sapiens | 1 | ALA4382285 | cell-based format | Scientific Literature | |
14. | ALA4385403 | B | Effect on voltage-dependent activation of rat KCNQ2 expressed in CHOK1 cells assessed as negative shift in current activation curve at 10 uM by whole cell patch clamp assay | Rattus norvegicus | 3 | ALA4382285 | cell-based format | Scientific Literature | |
15. | ALA4385404 | B | Effect on voltage-dependent activation of human KCNQ4 expressed in CHOK1 cells assessed as negative shift in current activation curve at 10 uM by whole cell patch clamp assay | Homo sapiens | 3 | ALA4382285 | cell-based format | Scientific Literature |