# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4423476 | F | Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Mus musculus | 13 | cell-based format | Scientific Literature | ||
2. | ALA4423477 | F | Antiproliferative activity against mouse B-ALL BCR-ABL double knockout cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Mus musculus | 13 | cell-based format | Scientific Literature | ||
3. | ALA4423478 | F | Antiproliferative activity against human NALM6 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
4. | ALA4423479 | F | Antiproliferative activity against human UOCB1 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
5. | ALA4423480 | F | Antiproliferative activity against human KOPN8 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
6. | ALA4423481 | F | Antiproliferative activity against human SUP-B15 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
7. | ALA4423482 | F | Antiproliferative activity against human MV411 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
8. | ALA4423483 | F | Antiproliferative activity against human K562 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
9. | ALA4423484 | T | Therapeutic index, ratio of EC50 for human BJ cells to EC50 for mouse B-ALL cells expressing wild type BCR-ABL | 13 | assay format | Scientific Literature | |||
10. | ALA4423485 | F | Antiproliferative activity against human BJ assessed as cell viability after 72 hrs by CellTiter-Glo assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
11. | ALA4423486 | A | Half life in mouse microsomes | Mus musculus | 4 | microsome format | Scientific Literature | ||
12. | ALA4423487 | A | Intrinsic clearance in mouse microsomes | Mus musculus | 4 | microsome format | Scientific Literature | ||
13. | ALA4423488 | A | Half life in human microsomes | Homo sapiens | 4 | microsome format | Scientific Literature | ||
14. | ALA4423489 | A | Intrinsic clearance in human microsomes | Homo sapiens | 4 | microsome format | Scientific Literature | ||
15. | ALA4423490 | A | Half life in simulated gastric fluid | 4 | assay format | Scientific Literature | |||
16. | ALA4423491 | A | Permeability of compound at pH 7.4 by PAMPA | 7 | assay format | Scientific Literature | |||
17. | ALA4423492 | A | Apparent permeability of compound form apical to basolateral side in human Caco2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
18. | ALA4423493 | A | Apparent permeability of compound form basolateral to apical side in human Caco2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
19. | ALA4423494 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in human Caco2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
20. | ALA4423495 | A | Protein binding in mouse plasma | Mus musculus | 4 | cell-free format | Scientific Literature |