| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4407501 | B | Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluorescence based enzyme immunoassay | Ovis aries | 8 | single protein format | Scientific Literature | ||
| 2. | ALA4407502 | B | Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluorescence based enzyme immunoassay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 3. | ALA4407503 | B | Selectivity index, ratio of IC50 for ovine COX1 to IC50 for recombinant human COX2 | 8 | assay format | Scientific Literature | |||
| 4. | ALA4407504 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability up to 50 uM incubated of WST assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4407505 | A | Cytotoxicity against rat Ac2F cells assessed as reduction in cell viability up to 50 uM incubated of WST assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4407506 | A | Cytotoxicity against mouse L929 cells assessed as reduction in cell viability up to 50 uM incubated of WST assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4407507 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as downregulation of LPS-stimulated iNOS protein expression pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4407508 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as downregulation of LPS-stimulated COX2 protein expression pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4407511 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as downregulation of LPS-stimulated iNOS protein expression at 20 uM pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4407512 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as downregulation of LPS-stimulated COX2 protein expression at 20 uM pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4407513 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-stimulated NO production pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by Griess reagent based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4407514 | B | Inhibition of COX2 in mouse RAW264.7 cells assessed as decrease in LPS-stimulated PGE2 production pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4407515 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as decrease in LPS-stimulated TNFalpha production pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4407516 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as decrease in LPS-stimulated IL6 production pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by sandwich ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4407517 | B | Inhibition of LPS-stimulated NFkappaB p65 nuclear translocation in mouse RAW264.7 cells retreated for 1 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4407518 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-stimulated ROS production pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by DCFH-DA dye based fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4407519 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-stimulated ROS production at 20 uM pretreated for 1 hrs followed by LPS addition and measured after 24 hrs by DCFH-DA dye based fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4407520 | B | Inhibition of LPS-stimulated IKK phosphorylation in mouse RAW264.7 cells at 5 to 20 uM pretreated for 1 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4407521 | B | Inhibition of LPS-stimulated IKK phosphorylation in mouse RAW264.7 cells assessed as decrease in IkappaBalpha phosphorylation level at 5 to 20 uM pretreated for 1 hrs followed by LPS addition and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4407522 | B | Inhibition of LPS-induced NFkappaB p65 nuclear translocation in mouse RAW264.7 cells at 20 uM preincubated for 1 hrs followed by LPS-stimulation and measured after 24 hrs by DAPI staining based confocal microscopic method | Mus musculus | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!