#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4345394	B	Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS SAM-PARP domain (1024 to 1327 residues) expressed in Escherichia coli assessed as reduction in auto-PARylation preincubated for 10 mins followed by biotinylated-NAD+ addition and measured after 45 mins by ELISA	Homo sapiens	36	ALA4342498	assay format	Scientific Literature
2.	ALA4345395	B	Inhibition of recombinant human N-terminal TEV cleavage site-fused/FLAG-poly his-tagged TNKS2 ARC5-SAM-PARP domain (613 to 1166 residues) expressed in Escherichia coli assessed as reduction in auto-PARylation preincubated for 10 mins followed by biotinylated-NAD+ addition and measured after 45 mins by ELISA	Homo sapiens	36	ALA4342498	assay format	Scientific Literature
3.	ALA4345396	B	Inhibition of TNKS/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay	Homo sapiens	36	ALA4342498	cell-based format	Scientific Literature
4.	ALA4345397	B	Inhibition of TNKS/TNKS2 (unknown origin) expressed in human DLD1 cells assessed as reduction in Wnt-signaling measured after 24 hrs by TCF-luciferase reporter gene assay	Homo sapiens	36	ALA4342498	cell-based format	Scientific Literature
5.	ALA4345398	F	Antiproliferative activity against human COLO320DM cells assessed as inhibition of cell growth measured after 4 days by CellTiter-Glo assay	Homo sapiens	36	ALA4342498	cell-based format	Scientific Literature
6.	ALA4345399	P	Aqueous solubility of the compound in pH 7.4 phosphate buffer saline at 200 uM incubated for 1 hr under shaking condition by UV spectra analysis		29	ALA4342498	small-molecule physicochemical format	Scientific Literature
7.	ALA4345400	A	Permeability of the compound measured after 4 hrs by PAMPA		6	ALA4342498	assay format	Scientific Literature
8.	ALA4345401	A	Stability in mouse liver microsomes assessed as parent compound remaining at 1 uM measured after 30 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	4	ALA4342498	microsome format	Scientific Literature
9.	ALA4345402	A	Stability in mouse liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Mus musculus	29	ALA4342498	microsome format	Scientific Literature
10.	ALA4345403	A	Stability in rat liver microsomes assessed as parent compound remaining at 1 uM measured after 30 mins in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	5	ALA4342498	microsome format	Scientific Literature
11.	ALA4345404	A	Stability in rat liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Rattus norvegicus	5	ALA4342498	microsome format	Scientific Literature
12.	ALA4345405	A	Stability in human liver microsomes assessed as parent compound remaining at 1 uM measured after 30 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	4	ALA4342498	microsome format	Scientific Literature
13.	ALA4345406	A	Stability in human liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by LC-MS/MS analysis	Homo sapiens	29	ALA4342498	microsome format	Scientific Literature
14.	ALA4345407	A	Protein binding in human plasma assessed as unbound fraction at 1 uM measured after 24 hrs by LC-MS/MS analysis	Homo sapiens	6	ALA4342498	cell-free format	Scientific Literature
15.	ALA4345408	A	Protein binding in mouse plasma assessed as unbound fraction at 1 uM measured after 24 hrs by LC-MS/MS analysis	Mus musculus	6	ALA4342498	cell-free format	Scientific Literature
16.	ALA4345409	A	Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in MDCK2-MDR1 cells	Canis lupus familiaris	28	ALA4342498	cell-based format	Scientific Literature
17.	ALA4345410	A	Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in MDCK2 cells	Canis lupus familiaris	28	ALA4342498	cell-based format	Scientific Literature
18.	ALA4345411	A	Net efflux ratio of permeability across basolateral to apical side over apical to basolateral side in MDCK2-MDR1 cells to MDCK2 cells	Canis lupus familiaris	26	ALA4342498	cell-based format	Scientific Literature
19.	ALA4345414	A	Tmax in ICR mouse at 50 mg/kg, ip	Mus musculus	2	ALA4342498	organism-based format	Scientific Literature
20.	ALA4345415	A	Cmax in ICR mouse at 50 mg/kg, ip	Mus musculus	2	ALA4342498	organism-based format	Scientific Literature