# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321374 | Functional | Antiproliferative activity against human Rec1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | ALA4316622 | cell-based format | Scientific Literature | |
2. | ALA4321375 | Functional | Antiproliferative activity against human JeKo1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | ALA4316622 | cell-based format | Scientific Literature | |
3. | ALA4321376 | Functional | Antiproliferative activity against human Maver1 cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | ALA4316622 | cell-based format | Scientific Literature | |
4. | ALA4321377 | Functional | Antiproliferative activity against human Z138 cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | ALA4316622 | cell-based format | Scientific Literature | |
5. | ALA4321378 | Functional | Antiproliferative activity against human Mino cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | ALA4316622 | cell-based format | Scientific Literature | |
6. | ALA4321379 | Binding | Inhibition of human BTK assessed as remaining kinase activity at 1 uM using Cdc2 peptide KVEKIGEGTYGVVYK substrate and [gamma-33P]-ATP incubated for 40 mins by radiometric protein kinase assay | Homo sapiens | 28 | ALA4316622 | single protein format | Scientific Literature | |
7. | ALA4321380 | ADME | Half life in human liver microsomes further incubated of 5 to 60 mins in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 5 | ALA4316622 | microsome format | Scientific Literature | |
8. | ALA4321381 | ADME | Intrinsic clearance in human liver microsomes further incubated of 5 to 60 mins in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 5 | ALA4316622 | microsome format | Scientific Literature | |
9. | ALA4321382 | ADME | Hepatic clearance in human liver microsomes further incubated of 5 to 60 mins in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 5 | ALA4316622 | microsome format | Scientific Literature | |
10. | ALA4321383 | ADME | Stability in human liver microsomes assessed as compound remaining incubated of 60 mins in presence of NADPH regenerating system by LC/MS analysis | Homo sapiens | 5 | ALA4316622 | microsome format | Scientific Literature |