| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4411980 | A | Negative inotropic activity in guinea pig spontaneously beating spontaneously beating right atrium assessed as decrease in developed tension | Cavia porcellus | 8 | tissue-based format | Scientific Literature | ||
| 2. | ALA4411983 | A | Negative inotropic activity in guinea pig left atrium assessed as decrease in developed tension at 10'-5 M relative to control | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 3. | ALA4411985 | A | Negative inotropic activity in guinea pig left atrium assessed as decrease in developed tension | Cavia porcellus | 10 | tissue-based format | Scientific Literature | ||
| 4. | ALA4411986 | A | Negative inotropic activity in guinea pig spontaneously beating right atrium assessed as decrease in developed tension at 10'-5 M | Cavia porcellus | 4 | tissue-based format | Scientific Literature | ||
| 5. | ALA4411990 | A | Negative chronotropic activity in guinea pig spontaneously beating right atrium assessed as decrease in atrial rate at 10'-5 M | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 6. | ALA4411991 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig aortic strips at 5 x 10'-5 M relative to control | Cavia porcellus | 8 | tissue-based format | Scientific Literature | ||
| 7. | ALA4411994 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig ileum at 5 x 10'-5 M relative to control | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
| 8. | ALA4411995 | A | Inhibition of calcium-induced contraction in K+-depolarized guinea pig ileum | Cavia porcellus | 10 | tissue-based format | Scientific Literature | ||
| 9. | ALA4411999 | B | Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level at 10 uM after 10 mins by Fluo-4 dye-based fluorescence assay relative to control | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 10. | ALA4412000 | B | Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA4412001 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 10 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4412002 | B | Inhibition of GSK3beta (unknown origin) pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured after 1 hr by TR-FRET assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 13. | ALA4412003 | B | Inhibition of GSK3beta (unknown origin) assessed as residual activity at 3.12 uM pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured after 1 hr by TR-FRET assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4412004 | B | Inhibition of GSK3beta (unknown origin) assessed as residual activity at 50 uM pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured after 1 hr by TR-FRET assay relative to control | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA4412005 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 30 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature |
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