#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4430591	B	Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assay	Homo sapiens	134		cell-based format	Scientific Literature
2.	ALA4430592	B	Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 20 nM GnRH-induced NFAT activation pre-incubated for 1 hr before GnRH stimulation and measured after 6 hrs by luciferase reporter gene assay	Homo sapiens	80		cell-based format	Scientific Literature
3.	ALA4430593	A	Inhibition of human recombinant CYP3A4 expressed in baculosomes at 10 uM incubated for 30 mins using BOMR substrate by fluorescence based assay	Homo sapiens	17		assay format	Scientific Literature
4.	ALA4430594	B	Displacement of [125I]D-Trp6-LHRH from monkey GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assay	Macaca mulatta	2		cell-based format	Scientific Literature
5.	ALA4430595	B	Displacement of [125I]D-Trp6-LHRH from rat GnRH receptor expressed in HEK293 cell membranes incubated for 1 hr by competitive binding assay	Rattus norvegicus	2		cell-based format	Scientific Literature
6.	ALA4430596	B	Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1 nM GnRH-induced NFAT activation pre-incubated for 1 hr before GnRH stimulation and measured after 6 hrs by luciferase reporter gene assay	Homo sapiens	2		cell-based format	Scientific Literature
7.	ALA4430597	B	Antagonist activity against monkey GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 10 nM GnRH-induced NFAT activation pre-incubated for 1 hr before GnRH stimulation and measured after 6 hrs by luciferase reporter gene assay	Macaca mulatta	2		cell-based format	Scientific Literature
8.	ALA4430598	B	Antagonist activity against rat GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 1 nM GnRH-induced NFAT activation pre-incubated for 1 hr before GnRH stimulation and measured after 6 hrs by luciferase reporter gene assay	Rattus norvegicus	2		cell-based format	Scientific Literature
9.	ALA4430599	B	Antagonist activity against human GnRH receptor expressed in HEK293 cells assessed as reduction in ERK1/2 phosphorylation pre-incubated for 5 mins before LHRH stimulation for 5 mins by chemiluminescence based assay	Homo sapiens	2		cell-based format	Scientific Literature
10.	ALA4430600	F	Antagonist activity against human GnRH receptor expressed in human Chem1 cells assessed as inhibition of LHRH-induced calcium flux by FLIPR assay	Homo sapiens	2		cell-based format	Scientific Literature
11.	ALA4430601	B	Selectivity index, ratio of IC50 for antagonist activity against monkey GnRH receptor expressed in HEK293 cells to IC50 for antagonist activity against human GnRH receptor expressed in HEK293 cells		1		cell-based format	Scientific Literature
12.	ALA4430602	B	Selectivity index, ratio of IC50 for antagonist activity against rat GnRH receptor expressed in HEK293 cells to IC50 for antagonist activity against human GnRH receptor expressed in HEK293 cells		1		cell-based format	Scientific Literature