# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4391032 | B | Inhibition of EthR2 in Mycobacterium tuberculosis assessed as potentiation of ETH bioactivation up to 30 uM using 0.1 ug/ml ETH | Mycobacterium tuberculosis | 9 | ALA4390646 | assay format | Scientific Literature | |
2. | ALA4391033 | B | Inhibition of recombinant Mycobacterium tuberculosis EthR2 expressed in golden hamster BHK21 cells assessed as reduction in EthR2 and DNA interaction measured after 48 hrs by p-nitrophenyl phosphate based SEAP reporter gene assay | Mycobacterium tuberculosis | 24 | ALA4390646 | cell-based format | Scientific Literature | |
3. | ALA4391034 | B | Binding affinity to recombinant Mycobacterium tuberculosis EthR2 assessed as change in melting temperature at 20 uM by SYPRO Orange dye based fluorescence thermal shift assay | Mycobacterium tuberculosis | 23 | ALA4390646 | assay format | Scientific Literature | |
4. | ALA4391035 | B | Binding affinity to recombinant Mycobacterium tuberculosis EthR2 assessed as change in melting temperature at 1 mM by Nano Orange dye based fluorescence thermal shift assay | Mycobacterium tuberculosis | 5 | ALA4390646 | assay format | Scientific Literature | |
5. | ALA4391036 | B | Binding affinity to Mycobacterium tuberculosis EthR at 30 uM by mammalian reporter assay | Mycobacterium tuberculosis | 1 | ALA4390646 | single protein format | Scientific Literature |