| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4359586 | B | Displacement of Alexa Fluor 647-labeled ligand from BRD4 BD1 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assay | Homo sapiens | 51 | ALA4354881 | single protein format | Scientific Literature | |
| 2. | ALA4359587 | B | Selectivity ratio of IC50 for displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) to IC50 for displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) | Homo sapiens | 24 | ALA4354881 | assay format | Scientific Literature | |
| 3. | ALA4359588 | B | Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-FRET assay | Homo sapiens | 51 | ALA4354881 | single protein format | Scientific Literature | |
| 4. | ALA4359589 | B | Displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) measured after 30 mins by TR-FRET assay | Homo sapiens | 51 | ALA4354881 | single protein format | Scientific Literature | |
| 5. | ALA4359590 | P | Kinetic solubility of the compound by CLND method | 22 | ALA4354881 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4359591 | P | Lipophilicity, log D of the compound at pH 7.4 by chromatographic method | 51 | ALA4354881 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4359593 | A | Permeability of the compound by artificial lipid membrane-based method | 11 | ALA4354881 | assay format | Scientific Literature | ||
| 8. | ALA4359594 | B | Displacement of Alexa Fluor 647-labeled ligand from BRD4 BD2 (unknown origin) measured after 30 mins by TR-FRET assay | Homo sapiens | 3 | ALA4354881 | single protein format | Scientific Literature | |
| 9. | ALA4359595 | B | Selectivity ratio of IC50 for displacement of Alexa Fluor 647-labeled ligand from BRD4 BD1 Y390A mutant (1 to 477 residue) (unknown origin) to IC50 for displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 10. | ALA4359596 | B | Selectivity ratio of IC50 for displacement of Alexa Fluor 647-labeled ligand from BRD4 BD2 (unknown origin) to IC50 for displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 11. | ALA4359597 | B | Binding affinity to human partial length ATAD2A (Q981 to R1108 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 12. | ALA4359598 | B | Binding affinity to human partial length ATAD2B (Q955 to R1082 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 13. | ALA4359599 | B | Binding affinity to human partial length BAZ2A (M1792 to L1905 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 14. | ALA4359600 | B | Binding affinity to human partial length BRD1 (E556 to A688 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 15. | ALA4359601 | B | Binding affinity to human partial length BRPF3 (E588 to G701 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 16. | ALA4359602 | B | Binding affinity to human partial length CECR2 (P423 to D543 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 3 | ALA4354881 | assay format | Scientific Literature | |
| 17. | ALA4359603 | B | Binding affinity to human partial length GCN5L2 (E726 to K837 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 3 | ALA4354881 | assay format | Scientific Literature | |
| 18. | ALA4359604 | B | Binding affinity to human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 3 | ALA4354881 | assay format | Scientific Literature | |
| 19. | ALA4359605 | B | Binding affinity to human partial length TAF1L bromodomain 2 (Q1523 to D1654 residues) expressed in bacterial expression system by BROMOscan assay | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature | |
| 20. | ALA4359606 | B | Selectivity ratio of Kd for binding affinity to human partial length ATAD2B (Q955 to R1082 residues) expressed in bacterial expression system to Kd for Binding affinity to human partial length ATAD2A (Q981 to R1108 residues) expressed in bacterial expression system | Homo sapiens | 1 | ALA4354881 | assay format | Scientific Literature |
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