# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418661 | B | Binding affinity to Max in human P493-6 cells assessed as induction of perturbation in transcriptional programs after 45 mins | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
2. | ALA4418662 | B | Inhibition of Myc (unknown origin) expressed in HEK293T cells incubated for 16 hrs by firefly/renilla luciferase reporter gene assay | Homo sapiens | 20 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
3. | ALA4418663 | F | Cytotoxicity against human ST486 cells assessed as reduction in cell viability incubated for 3 days by CellTiter-Glo assay | Homo sapiens | 2 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
4. | ALA4418668 | F | Cytotoxicity against human P493-6 cells with where Myc is in ON- condition assessed as reduction in cell viability incubated for 3 days by CellTiter-Glo assay | Homo sapiens | 9 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
5. | ALA4418669 | A | Cytotoxicity against human P493-6 cells with where Myc is in OFF- condition assessed as reduction in cell viability incubated for 3 days by CellTiter-Glo assay | Homo sapiens | 9 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
6. | ALA4418676 | B | Binding affinity to Max in human P493-6 cells at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
7. | ALA4418677 | B | Binding affinity to c-Myc in human P493-6 cells at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
8. | ALA4418678 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Rcor1 level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
9. | ALA4418679 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Atg16l1 level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
10. | ALA4418680 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Nacc2 level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
11. | ALA4418681 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Yaf2 level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
12. | ALA4418682 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Mxd4 level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
13. | ALA4418683 | B | Binding affinity to Max in human P493-6 cells assessed as effect on Max interactome by measuring perturbation in Myc level at 10 mM incubated for 30 mins by immunoprecipitation based assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
14. | ALA4418684 | B | Inhibition of c-Myc/Max heterodimer interaction in human P493-6 cells by electrophoretic mobility shift assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
15. | ALA4418685 | B | Induction of Max homodimer stabilization in human P493-6 cells assessed as increase in Max homodimer binding to DNA by electrophoretic mobility shift assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
16. | ALA4418686 | B | Induction of Max homodimer stabilization in human P493-6 cells assessed as increase in Max homodimer level by fPLC relative to untreated control | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
17. | ALA4418687 | B | Binding affinity to Max in human P493-6 cells assessed as decrease in Myc protein levels | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
18. | ALA4418688 | B | Binding affinity to Max in human P493-6 cells assessed as decrease in Myc protein levels at 10 uM in presence of 10 uM proteasome inhibitor MG132 | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
19. | ALA4418689 | B | Binding affinity to Max in human P493-6 cells assessed as decrease in Myc transcript levels by qPCR analysis | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data | |
20. | ALA4418690 | F | Cytotoxicity against human P3HR1 cells assessed as reduction in cell viability incubated for 3 days by CellTiter-Glo assay | Homo sapiens | 1 | ALA4418487 | cell-based format | Patent Bioactivity Data |