# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346015 | B | Inhibition of rat nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Rattus norvegicus | 37 | assay format | Scientific Literature | ||
2. | ALA4346016 | B | Inhibition of human nNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Homo sapiens | 22 | assay format | Scientific Literature | ||
3. | ALA4346017 | A | Inhibition of mouse iNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Mus musculus | 21 | assay format | Scientific Literature | ||
4. | ALA4346018 | A | Inhibition of human eNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Homo sapiens | 20 | assay format | Scientific Literature | ||
5. | ALA4346019 | U | Selectivity index, ratio of Ki for rat nNOS expressed in Escherichia coli expression system to Ki for mouse iNOS expressed in Escherichia coli expression system | 21 | assay format | Scientific Literature | |||
6. | ALA4346020 | U | Selectivity index, ratio of Ki for human eNOS expressed in Escherichia coli expression system to Ki for human nNOS expressed in Escherichia coli expression system | Homo sapiens | 20 | assay format | Scientific Literature | ||
7. | ALA4346021 | A | Inhibition of human iNOS expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
8. | ALA4346022 | U | Selectivity index, ratio of Ki for human iNOS expressed in Escherichia coli expression system to Ki for human nNOS expressed in Escherichia coli expression system | Homo sapiens | 8 | assay format | Scientific Literature | ||
9. | ALA4346023 | B | Inhibition of rat nNOS D597N mutant expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Rattus norvegicus | 6 | assay format | Scientific Literature | ||
10. | ALA4346024 | B | Inhibition of rat nNOS M336V/D597N double mutant expressed in Escherichia coli expression system assessed as reduction in NO production in presence of L-arginine measured for 30 sec by hemoglobin capture assay | Rattus norvegicus | 6 | assay format | Scientific Literature | ||
11. | ALA4346025 | B | Selectivity index, ratio of Ki for rat nNOS expressed in Escherichia coli expression system to Ki for rat nNOS D597N mutant expressed in Escherichia coli expression system | Rattus norvegicus | 6 | assay format | Scientific Literature | ||
12. | ALA4346026 | B | Selectivity index, ratio of Ki for rat nNOS expressed in Escherichia coli expression system to Ki for rat nNOS M336V/D597N double mutant expressed in Escherichia coli expression system | Rattus norvegicus | 6 | assay format | Scientific Literature | ||
13. | ALA4346028 | A | Effective permeability of compound in PBS buffer at pH 7.4 at 200 uM incubated for 17 hrs by PAMPA-BBB assay | 8 | assay format | Scientific Literature |