| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4388619 | B | Protac activity at CRBN/BTK C481S mutant in human MCL cells assessed as induction of BTK C481S mutant degradation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4388620 | B | Protac activity at CRBN/BTK C481S mutant in human MCL cells assessed as induction of BTK C481S mutant degradation at 500 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4388621 | B | Protac activity at CRBN/BTK C481S mutant in human MM cells assessed as induction of BTK C481S mutant protein degradation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4388622 | B | Protac activity at CRBN/BTK C481S mutant in human MM cells assessed as induction of BTK C481S mutant protein degradation at 500 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5104671 | B | PROTAC activity at CRBN/BTK C481S mutant transfected in human HeLa cells assessed as induction of BTK C481S degradation incubated for 4 days by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5124393 | B | PROTAC activity at CRBN/BTK (unknown origin) assessed as BTK degradation | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 7. | ALA5124396 | B | Induction of degradation of BTK in human Ramos cells at 10 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5124397 | B | Induction of degradation of BTK in human Ramos cells at 100 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5124398 | F | Inhibition of cell proliferation in human HBL1 cells harboring Ibrutinib-resistant BTK C481S mutant assessed as cell growth inhibition | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA5243526 | B | Induction of BTK (unknown origin) degradation in Burkitts lymphoma cells at 10 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5243527 | B | Induction of BTK (unknown origin) degradation in Burkitts lymphoma cells at 100 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5243528 | F | Antiproliferative activity against human HBL cells assessed as inhibition of cell growth | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5246073 | F | Antiproliferative activity against human HBL1 cells expressing BTK C481S mutant assessed as growth inhibition | Homo sapiens | 2 | cell-based format | Scientific Literature |
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