| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4403614 | B | Inhibition of Beta-lactamase OXA-48 in Enterobacteriaceae assessed as potentiation of meropenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 2. | ALA4403615 | B | Inhibition of Beta-lactamase OXA-48 in Enterobacteriaceae assessed as potentiation of imipenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 3. | ALA4403616 | B | Inhibition of Beta-lactamase KPC in Enterobacteriaceae assessed as potentiation of meropenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 4. | ALA4403617 | B | Inhibition of Beta-lactamase KPC in Enterobacteriaceae assessed as potentiation of imipenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 5. | ALA4403618 | B | Inhibition of OXA-181 in Enterobacteriaceae assessed as potentiation of meropenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 6. | ALA4403619 | B | Inhibition of OXA-181 in Enterobacteriaceae assessed as potentiation of imipenem-induced antibacterial activity by CLSI based agar dilution method | Enterobacteriaceae | 1 | ALA4402541 | assay format | Scientific Literature | |
| 7. | ALA4706276 | B | Inhibition of beta lactamase AmpC in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Enterobacter cloacae | 15 | ALA4699665 | assay format | Scientific Literature | |
| 8. | ALA4706277 | B | Inhibition of beta lactamase CTXM-15 in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Enterobacter cloacae | 15 | ALA4699665 | assay format | Scientific Literature | |
| 9. | ALA4706278 | B | Inhibition of beta lactamase TEM-1 in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Enterobacter cloacae | 15 | ALA4699665 | assay format | Scientific Literature | |
| 10. | ALA4706279 | B | Inhibition of beta lactamase OXA-48 in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Enterobacter cloacae | 15 | ALA4699665 | assay format | Scientific Literature | |
| 11. | ALA4706280 | B | Inhibition of beta lactamase KPC-2 in Enterobacter cloacae assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Enterobacter cloacae | 15 | ALA4699665 | assay format | Scientific Literature | |
| 12. | ALA4706281 | B | Inhibition of bacteria beta lactamase OXA-23 assessed as decrease in enzyme activity using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured for 10 mins by fluorescence plate reader analysis | Bacteria | 15 | ALA4699665 | assay format | Scientific Literature | |
| 13. | ALA4706282 | F | Potentiation of meropenem-induced antibacterial activity against Enterobacter cloacae expressing TEM-1/KPC-2 assessed as meropenem MIC at 4 ug/ml by broth microdilution method (Rvb = 8 ug/ml) | Enterobacter cloacae | 15 | ALA4699665 | organism-based format | Scientific Literature | |
| 14. | ALA4706283 | F | Potentiation of meropenem-induced antibacterial activity against Klebsiella pneumoniae expressing TEM-OSBL/CTX-M-14/OXA-48 assessed as meropenem MIC at 4 ug/ml by broth microdilution method (Rvb = 16 ug/ml) | Klebsiella pneumoniae | 15 | ALA4699665 | organism-based format | Scientific Literature | |
| 15. | ALA4706284 | F | Potentiation of meropenem-induced antibacterial activity against Klebsiella pneumoniae expressing TEM-1/SHV-11/KPC-3 assessed as meropenem MIC at 4 ug/ml by broth microdilution method (Rvb = 128 ug/ml) | Klebsiella pneumoniae | 15 | ALA4699665 | organism-based format | Scientific Literature | |
| 16. | ALA4706285 | F | Potentiation of meropenem-induced antibacterial activity against Klebsiella pneumoniae expressing SHV-11/OXA-121 assessed as meropenem MIC at 4 ug/ml by broth microdilution method (Rvb = 16 ug/ml) | Klebsiella pneumoniae | 15 | ALA4699665 | organism-based format | Scientific Literature | |
| 17. | ALA4706286 | F | Potentiation of meropenem-induced antibacterial activity against Acinetobacter baumannii expressing OXA-23 assessed as meropenem MIC at 4 ug/ml by broth microdilution method (Rvb = 32 ug/ml) | Acinetobacter baumannii | 15 | ALA4699665 | organism-based format | Scientific Literature | |
| 18. | ALA4706292 | B | Inhibition of beta lactamase KPC in carbapenem-resistant Enterobacter assessed as meropenem-induced antibacterial activity by measuring meropenem MIC50 at 4 ug/ml by broth microdilution method (Rvb >32 ug/ml) | Enterobacter | 2 | ALA4699665 | assay format | Scientific Literature | |
| 19. | ALA4706293 | B | Inhibition of beta lactamase KPC in carbapenem-resistant Enterobacter assessed as meropenem-induced antibacterial activity by measuring meropenem MIC90 at 4 ug/ml by broth microdilution method (Rvb >32 ug/ml) | Enterobacter | 2 | ALA4699665 | assay format | Scientific Literature | |
| 20. | ALA4706294 | B | Inhibition of beta lactamase KPC in carbapenem-resistant Enterobacter assessed as meropenem minimum concentration required for antibacterial activity at 4 ug/ml by broth microdilution method (Rvb = 4 ug/ml) | Enterobacter | 2 | ALA4699665 | assay format | Scientific Literature |
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