# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4397963 | B | Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed by substrate addition and and measured after 30 mins by fluorescence based assay | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
2. | ALA4397964 | B | Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
3. | ALA4397965 | B | Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
4. | ALA4397966 | B | Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
5. | ALA4397967 | F | Induction of apoptosis in human A549 cells assessed as viable cells at 1 uM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 98%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA4397968 | F | Antiproliferative activity against human A549 cells assessed as growth inhibition at 2 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
7. | ALA4397969 | F | Antiproliferative activity against human A549 cells assessed as growth inhibition at 8 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
8. | ALA4397970 | F | Antiproliferative activity against human A375 cells assessed as growth inhibition at 2 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
9. | ALA4397971 | F | Antiproliferative activity against human A375 cells assessed as growth inhibition at 8 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
10. | ALA4397972 | F | Antiproliferative activity against human SMMC7721 cells assessed as growth inhibition at 2 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
11. | ALA4397973 | F | Antiproliferative activity against human SMMC7721 cells assessed as growth inhibition at 8 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
12. | ALA4397974 | F | Antiproliferative activity against human HCT116 cells assessed as growth inhibition at 2 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
13. | ALA4397975 | F | Antiproliferative activity against human HCT116 cells assessed as growth inhibition at 8 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
14. | ALA4397976 | F | Antiproliferative activity against human HeLa cells assessed as growth inhibition at 2 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
15. | ALA4397977 | F | Antiproliferative activity against human HeLa cells assessed as growth inhibition at 8 uM after 72 hrs by CCK-8 assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
16. | ALA4397978 | F | Antiproliferative activity against human A549 cells assessed as decrease in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
17. | ALA4397979 | F | Antiproliferative activity against human A375 cells assessed as decrease in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
18. | ALA4397980 | F | Antiproliferative activity against human SMMC7721 cells assessed as decrease in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
19. | ALA4397981 | F | Antiproliferative activity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
20. | ALA4397982 | F | Antiproliferative activity against human HeLa cells assessed as decrease in cell viability after 72 hrs by CCK-8 assay | Homo sapiens | 18 | cell-based format | Scientific Literature |