# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4350831 | F | Antiproliferative activity against patient-derived GBM cells assessed as cell viability after 48 hrs by 5-Ethynyl-2'-deoxyuridine incorporation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4350832 | F | Potency index, ratio of crizotinib EC50 to compound EC50 for antiproliferative activity against patient-derived GBM cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA4350833 | F | Synergistic antiproliferative activity against patient-derived GBM cells assessed as cell viability after 48 hrs in presence of temozolomide by 5-Ethynyl-2'-deoxyuridine incorporation assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA4350834 | F | Potency index, ratio of crizotinib EC50 for antiproliferative activity against patient-derived GBM cells to compound EC50 for antiproliferative activity against patient-derived GBM cells in presence of temozolomide | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4350835 | F | Antiproliferative activity against patient-derived GBM cells assessed as reduction in cell viability after 48 hrs by 5-Ethynyl-2'-deoxyuridine incorporation assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4350836 | F | Potency index, ratio of crizotinib IC50 to compound IC50 for antiproliferative activity against patient-derived GBM cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA4350837 | F | Synergistic antiproliferative activity against patient-derived GBM cells assessed as reduction in cell viability after 48 hrs in presence of temozolomide by 5-Ethynyl-2'-deoxyuridine incorporation assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4350838 | F | Potency index, ratio of crizotinib IC50 for antiproliferative activity against patient-derived GBM cells to compound IC50 for antiproliferative activity against patient-derived GBM cells in presence of temozolomide | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4350839 | A | Substrate activity at OATP in patient-derived GBM cells assessed as compound uptake at 1 uM incubated for 1 hr in presence of OATP inhibitior sodium taurocholic acid by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4350840 | A | Substrate activity at OATP in patient-derived GBM cells assessed as compound uptake at 1 uM incubated for 1 hr in presence of OATP activator 3,4-Dihydroxybenzoic acid by fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4350841 | F | Cytotoxicity against patient-derived GBM cells assessed as LDH release after 96 hrs by spectrophotometric method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA4350842 | F | Selectivity ratio of EC50 for antiproliferative activity against patient-derived GBM cells to EC50 for antiproliferative activity against patient-derived GBM cells in presence of temozolomide | Homo sapiens | 2 | cell-based format | Scientific Literature |