| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4390487 | B | Inhibition of TRAF6 (unknown origin)-mediated NFkappaB activation expressed in human HeLaS3 cells harboring 3kappaB-tk-luc at 10 uM preincubated for 1 hr followed by Il1alpha-stimulation and measured after 3 hrs by dual-luciferase reporter gene assay relative to control | Homo sapiens | 2 | ALA4387775 | cell-based format | Scientific Literature | |
| 2. | ALA4390488 | B | Inhibition of TRAF6 (unknown origin)-mediated NFkappaB activation expressed in human HeLaS3 cells harboring 3kappaB-tk-luc at 10 uM preincubated for 1 hr followed by Il1alpha-stimulation and measured after 3 hrs in presence of DTT by dual-luciferase reporter gene assay relative to control | Homo sapiens | 10 | ALA4387775 | cell-based format | Scientific Literature | |
| 3. | ALA4390489 | F | Cytotoxicity against human HeLaS3 cells assessed as reduction in cell viability at 10 uM measured after 8 hrs in presence of DTT by MTT assay relative to control | Homo sapiens | 3 | ALA4387775 | cell-based format | Scientific Literature | |
| 4. | ALA4390490 | A | Prodrug conversion in human HeLaS3 assessed as NpSH formation at 10 uM | Homo sapiens | 4 | ALA4387775 | cell-based format | Scientific Literature |
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