| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4396706 | B | Agonist activity at PPARalpha in human Huh7 cells assessed as PPARA mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4396708 | B | Agonist activity at PPARalpha in human Huh7 cells assessed as SCD1 mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4396709 | B | Agonist activity at PPARalpha in human Huh7 cells assessed as SREBF1 mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4396711 | B | Agonist activity at PPARalpha in C57BL/6N mouse primary hepatocytes assessed as PPARA mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4396712 | B | Agonist activity at PPARalpha in C57BL/6N mouse primary hepatocytes assessed as SCD1 mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4396713 | B | Agonist activity at PPARalpha in C57BL/6N mouse primary hepatocytes assessed as SREBF1 mRNA expression at 50 uM measured after 18 hrs by qRT-PCR analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4396722 | F | Upregulation of PPARgamma gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4396724 | F | Upregulation of CEBPA gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4396726 | F | Upregulation of ACSL1 gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4396728 | F | Upregulation of CD36 gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA4396730 | F | Upregulation of FABP4 gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4396732 | F | Upregulation of PLIN1 gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4396734 | F | Upregulation of ADIPOQ gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA4396736 | F | Upregulation of ANGPTL4 gene expression in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient at 25 uM measured for 12 days by qRT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4396738 | F | Induction of adipocyte differentiation in human preadipocyte derived from Simpson-Golabi-Behmel syndrome (SGBS) patient assessed as lipid accumulation at 25 uM measured for 12 days by Oil red O staining based microscopic analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4721820 | B | Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4721821 | B | Agonist activity at recombinant human PPARgamma LBD (205 to 505 residues) expressed in African green monkey COS-1 cells incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4721822 | A | Cytotoxicity against African green monkey COS-1 cells assessed as cell viability at EC50 concentration for PPAR activation assay by LDH assay | Chlorocebus aethiops | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4721823 | A | Cytotoxicity against African green monkey COS-1 cells assessed as cell viability at EC50 concentration for PPAR activation assay by XTT assay | Chlorocebus aethiops | 5 | cell-based format | Scientific Literature | ||
| 20. | ALA4721824 | B | Agonist activity at recombinant human PPARalpha LBD (168 to 468 residues) expressed in African green monkey COS-1 cells at 25 to 50 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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