# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4421213 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay | Mus musculus | 12 | ALA4420080 | cell-based format | Patent Bioactivity Data | |
2. | ALA4477671 | B | Inhibition of His-tagged Bcl-xL/5-carboxyfluorescein-Bak (unknown origin) after 1 hr by fluorescence polarization assay | Homo sapiens | 14 | ALA4477185 | protein format | Scientific Literature | |
3. | ALA4477672 | B | Inhibition of His-tagged Mcl-1/5-carboxyfluorescein-Bid (unknown origin) after 1 hr by fluorescence polarization assay | Homo sapiens | 14 | ALA4477185 | protein format | Scientific Literature | |
4. | ALA4477673 | F | Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 7 | ALA4477185 | cell-based format | Scientific Literature | |
5. | ALA4731547 | F | Induction of autophagy-mediated apoptosis in human PC3 cells assessed as increase in cleave PARP level at 10 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
6. | ALA4731548 | F | Induction of autophagy-mediated apoptosis in human PC3 cells assessed as increase in cleave PARP level at 20 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
7. | ALA4731549 | F | Induction of autophagy in human PC3 cells assessed as increased of LC3-II level at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
8. | ALA4731550 | B | Inhibition of SUMO1 (unknown origin) assessed as reduction in SUMOylated RanGAP1 level at 50 uM incubated for 60 mins by western blot analysis | Homo sapiens | 28 | ALA4725472 | single protein format | Scientific Literature | |
9. | ALA4731551 | B | Inhibition of SUMO1 in human PC3 cells assessed as reduction in SUMOylation level at 10 to 20 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
10. | ALA4731552 | B | Inhibition of SUMO1 in human MDA-MB-231 cells assessed as reduction in SUMOylation level at 10 uM measured after 24 hrs by western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
11. | ALA4731553 | F | Induction of autophagy in human PC3 cells assessed as increased of LC3-II level at 20 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 5 | ALA4725472 | cell-based format | Scientific Literature | |
12. | ALA4731554 | F | Cytotoxicity against human PC3 cells assessed as cell death at 5 to 10 uM incubated for 24 hrs by crystal violet staining based spectrophotometric analysis | Homo sapiens | 4 | ALA4725472 | cell-based format | Scientific Literature | |
13. | ALA4731555 | F | Cytotoxicity against human MDA-MB-231 cells assessed as cell death at 10 to 20 uM incubated for 24 hrs by crystal violet staining based spectrophotometric analysis | Homo sapiens | 4 | ALA4725472 | cell-based format | Scientific Literature | |
14. | ALA4731559 | B | Inhibition of SUMO2 in human PC3 cells assessed as reduction in SUMOylation level at 10 uM measured after 24 hrs by western blot analysis | Homo sapiens | 4 | ALA4725472 | cell-based format | Scientific Literature |