| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4400289 | B | Displacement of [3H]methyl- N-alpha methylhistamine dihydrochloride from human recombinant H3 receptor expressed in CHOK1 cells measured after 30 mins by liquid scintillation counter method | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 2. | ALA4400290 | B | Displacement of [3H]methyl- N-alpha methylhistamine dihydrochloride from Sprague-Dawley rat cerebral cortex H3 receptor measured after 30 mins by scintillation counter method | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
| 3. | ALA4400291 | B | Displacement of [3H]quinuclidinyl benzilate from Wistar rat cortex muscarinic acetylcholine receptor by liquid scintillation counter method | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
| 4. | ALA4400294 | B | Inhibition of human ERG | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 5. | ALA4400295 | F | In vivo antagonist activity at Wistar rat H3 receptor assessed as inhibition of imetit-induced dipsogenia at 30 mg/kg, po for 30 mins followed by imetit administration at 3 mg/kg, sc, relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4400309 | F | In vivo antagonist activity at H3 receptor in ip dosed Wistar rat assessed as inhibition of imetit induced dipsogenia preincubated for 30 mins followed by imetit administration at 3 mg/kg,sc | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA5263166 | B | Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by ELISA analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 8. | ALA5263167 | B | Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS addition and measured after 60 mins by TopCount NXT based scintillation analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 9. | ALA5263168 | B | Binding affinity to Estrogen receptor beta (unknown origin) at 1 uM by displacement assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5263169 | B | Binding affinity to Estrogen receptor alpha (unknown origin) at 1 uM by displacement assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5263170 | B | Displacement of [3H]histamine from human histamine H4 receptors expressed in CHO-K1 cell membrane at 1 uM incubated for 30 mins by scintillation counter analysis relative to control | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 12. | ALA5263171 | B | Displacement of [3H]tiotidine from recombinant human histamine H2 receptor expressed in CHO-K1 cell membrane at 1 uM incubated for 45 mins by Scintillation counter analysis relative to control | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 13. | ALA5263172 | B | Displacement of [3H]pyrilamine from recombinant human histamine H1 receptor expressed in CHO-K1 cell membrane at 1 uM incubated for 30 mins by liquid scintillation counter analysis relative to control | Homo sapiens | 1 | cell membrane format | Scientific Literature | ||
| 14. | ALA5263173 | B | Displacement of [3H]quinuclidinyl benzilate from Wistar rat cortex muscarinic AChR at 1 uM by liquid scintillation counting analysis relative to control | Rattus norvegicus | 18 | tissue-based format | Scientific Literature | ||
| 15. | ALA5263176 | B | Displacement of [3H]quinuclidinyl benzilate from Wistar rat cortex muscarinic AChR assessed as inhibition constant by liquid scintillation counting analysis | Rattus norvegicus | 8 | tissue-based format | Scientific Literature | ||
| 16. | ALA5263177 | B | Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 30 mins by liquid scintillation analysis | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 17. | ALA5263178 | B | Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibition constant incubated for 30 mins by liquid scintillation counting analysis | Rattus norvegicus | 22 | cell membrane format | Scientific Literature |
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