# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4429876 | B | Inhibition of glycine transporter-1B in human JAR cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycine addition measured after 3 hrs by scintillation proximity assay | Homo sapiens | 33 | ALA4428077 | cell-based format | Scientific Literature | |
2. | ALA4429877 | B | Inhibition of human glycine transporter-2 expressed in HEK293 cells assessed as reduction in [14C]glycine uptake preincubated for 10 mins followed by [14C]glycine addition measured after 3 hrs by scintillation proximity assay | Homo sapiens | 34 | ALA4428077 | cell-based format | Scientific Literature | |
3. | ALA4429878 | A | Intrinsic clearance in human liver microsomes at 3 uM incubated up to 60 mins by LC-MS analysis | Homo sapiens | 8 | ALA4428077 | microsome format | Scientific Literature | |
4. | ALA4429879 | A | Intrinsic clearance in rat liver microsomes at 3 uM incubated up to 60 mins by LC-MS analysis | Rattus norvegicus | 8 | ALA4428077 | microsome format | Scientific Literature |