# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4431153 | B | Inhibition of recombinant sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 12 | ALA4428134 | single protein format | Scientific Literature | |
2. | ALA4431154 | B | Inhibition of sPLA2 in human plasma using 1-Hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphomethanol as substrate preincubated for 10 mins followed by substrate addition measured after 90 mins by fluorescence assay | Homo sapiens | 11 | ALA4428134 | cell-free format | Scientific Literature | |
3. | ALA4431156 | B | Inhibition of recombinant sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 11 | ALA4428134 | assay format | Scientific Literature | |
4. | ALA4431157 | B | Inhibition of recombinant sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate preincubated for 10 mins followed by substrate addition measured after 60 mins by colorimetric method | Homo sapiens | 11 | ALA4428134 | single protein format | Scientific Literature | |
5. | ALA4431162 | A | Intrinsic clearance in human hepatocytes at 1 uM assessed per million cells measured up to 60 mins | Homo sapiens | 6 | ALA4428134 | cell-based format | Scientific Literature | |
6. | ALA4431176 | B | Inhibition of human OATP1B1 expressed in HEK293 cells assessed as reduction in pivastatin uptake at 25 uM | Homo sapiens | 2 | ALA4428134 | cell-based format | Scientific Literature |