# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307005 | Binding | Inhibition of Akt1 (unknown origin) expressed in Escherichia coli using peptide as substrate incubated for 1 hr by HTRF assay | Homo sapiens | 18 | ALA4304777 | assay format | Scientific Literature | |
2. | ALA4307007 | Functional | Cytotoxicity against human OVCAR8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay | Homo sapiens | 18 | ALA4304777 | cell-based format | Scientific Literature | |
3. | ALA4307008 | Functional | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay | Homo sapiens | 18 | ALA4304777 | cell-based format | Scientific Literature | |
4. | ALA4307009 | Functional | Antiproliferative activity against human MM1S cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
5. | ALA4307010 | Functional | Antiproliferative activity against human RPMI8226 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
6. | ALA4307011 | Functional | Antiproliferative activity against human CEM/C1 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
7. | ALA4307012 | Functional | Antiproliferative activity against human MOLT4 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
8. | ALA4307013 | Functional | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
9. | ALA4307014 | Functional | Antiproliferative activity against human HUT78 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
10. | ALA4307015 | Functional | Antiproliferative activity against human JVM2 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
11. | ALA4307016 | Functional | Antiproliferative activity against human U937 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
12. | ALA4307017 | Functional | Antiproliferative activity against human CCRF-CEM cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
13. | ALA4307018 | Functional | Antiproliferative activity against human Mino cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
14. | ALA4307019 | Functional | Antiproliferative activity against human K562 cells assessed as reduction in cell viability | Homo sapiens | 3 | ALA4304777 | cell-based format | Scientific Literature | |
15. | ALA4307020 | Functional | Induction of apoptosis in human HCT116 cells assessed as apoptotic cells at 0.4 uM incubated for 72 hrs by annexin V - FITC and propidium iodide staining based flow cytometry (Rvb = 6.99 %) | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature | |
16. | ALA4307021 | Functional | Induction of apoptosis in human HCT116 cells assessed as apoptotic cells at 2 uM incubated for 72 hrs by annexin V - FITC and propidium iodide staining based flow cytometry (Rvb = 6.99 %) | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature | |
17. | ALA4307022 | Functional | Induction of apoptosis in human HCT116 cells assessed as apoptotic cells at 10 uM incubated for 72 hrs by annexin V - FITC and propidium iodide staining based flow cytometry (Rvb = 6.99 %) | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature | |
18. | ALA4307023 | Binding | Inhibition of Akt in human HCT116 cells assessed as reduction in GSK3beta phosphorylation after 72 hrs by Western blot analysis | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature | |
19. | ALA4307024 | Binding | Inhibition of Akt in human HCT116 cells assessed as reduction in PRAS40 phosphorylation after 72 hrs by Western blot analysis | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature | |
20. | ALA4307025 | Binding | Inhibition of Akt phosphorylation at Ser-473 and thr-308 in human HCT116 cells after 72 hrs by Western blot analysis | Homo sapiens | 2 | ALA4304777 | cell-based format | Scientific Literature |