# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4385012 | F | Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 10 uM measured after 48 hrs relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
2. | ALA4385013 | F | Inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 100 uM measured after 48 hrs relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
3. | ALA4385014 | A | Cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 10 uM relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
4. | ALA4385015 | A | Cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 100 uM relative to control | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
5. | ALA4385016 | U | Selectivity index, ratio of compound effect for cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 10 uM to compound effect for inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 10 uM | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
6. | ALA4385017 | U | Selectivity index, ratio of compound effect for cytotoxicity against non-stimulated mouse B16F10 cells assessed as cell viability at 100 uM to compound effect for inhibition of alpha-MSH-stimulated melanogenesis in mouse B16F10 cells assessed as melanin content at 100 uM | Mus musculus | 6 | ALA4382264 | cell-based format | Scientific Literature | |
7. | ALA4385018 | F | Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
8. | ALA4385019 | F | Cytotoxicity against human AZ-521 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
9. | ALA4385020 | F | Cytotoxicity against human SKBR3 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
10. | ALA4385021 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
11. | ALA4385022 | A | Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | ALA4382264 | cell-based format | Scientific Literature | |
12. | ALA4385023 | U | Selectivity index, ratio of IC50 for human W138 cells to IC50 for human A549 cells | Homo sapiens | 5 | ALA4382264 | assay format | Scientific Literature |