# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4309008 | B | Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 4 | ALA4308825 | cell-based format | Scientific Literature | |
2. | ALA4309009 | B | Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 6 | ALA4308825 | cell-based format | Scientific Literature | |
3. | ALA4309010 | B | Positive allosteric modulation of GluN2B receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 5 | ALA4308825 | cell-based format | Scientific Literature | |
4. | ALA4309011 | B | Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 4 | ALA4308825 | cell-based format | Scientific Literature | |
5. | ALA4423741 | B | Allosteric modulation of rat GluN2A expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
6. | ALA4423742 | B | Allosteric modulation of rat GluN2B expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
7. | ALA4423743 | B | Allosteric modulation of rat GluN2C expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
8. | ALA4423744 | B | Allosteric modulation of rat GluN2D expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
9. | ALA4423745 | B | Positive allosteric modulation of rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
10. | ALA4423746 | B | Positive allosteric modulation of rat GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
11. | ALA4423747 | B | Positive allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
12. | ALA4423748 | B | Positive allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
13. | ALA4423751 | P | Solubility of the compound at 100 uM | 45 | ALA4422636 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA4423752 | B | Agonist activity at rat GluN2A expressed in Xenopus laevis oocytes assessed effect on current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 23 | ALA4422636 | cell-based format | Scientific Literature | |
15. | ALA4423753 | B | Agonist activity at rat GluN2B expressed in Xenopus laevis oocytes assessed as effect on current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 23 | ALA4422636 | cell-based format | Scientific Literature | |
16. | ALA4423754 | B | Agonist activity at rat GluN2C expressed in Xenopus laevis oocytes assessed effect on current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 23 | ALA4422636 | cell-based format | Scientific Literature | |
17. | ALA4423755 | B | Agonist activity at rat GluN2D expressed in Xenopus laevis oocytes assessed as effect on current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 23 | ALA4422636 | cell-based format | Scientific Literature | |
18. | ALA4423756 | B | Positive allosteric modulation of rat GluN2A expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
19. | ALA4423757 | B | Positive allosteric modulation of rat GluN2B expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
20. | ALA4423758 | B | Positive allosteric modulation of rat GluN2C expressed in Xenopus laevis oocytes assessed as potentiation of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature |