# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4362317 | B | Inhibition of recombinant full length N-terminal His6 tagged human FYN expressed in baculovirus infected sf21 cells using KVEKIGEGTYGVVYK as substrate in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 2 | ALA4359870 | cell-based format | Scientific Literature | |
2. | ALA4362318 | B | Inhibition of LYN (unknown origin) using KVEKIGEGTYGVVYK as substrate in presence of [gamma33P]ATP as substrate in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 2 | ALA4359870 | single protein format | Scientific Literature | |
3. | ALA4362319 | B | Inhibition of BLK (unknown origin) using KVEKIGEGTYGVVYK as substrate in presence of [gamma33P]ATP as substrate in presence of [gamma33P]ATP by scintillation counting method | Homo sapiens | 2 | ALA4359870 | single protein format | Scientific Literature | |
4. | ALA4362320 | F | Antiproliferative activity against human DOHH2 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
5. | ALA4362321 | F | Antiproliferative activity against human Farage cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
6. | ALA4362322 | F | Antiproliferative activity against human SUDHL8 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
7. | ALA4362323 | F | Antiproliferative activity against human SUDHL6 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
8. | ALA4362324 | F | Antiproliferative activity against human HUT78 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
9. | ALA4362325 | F | Antiproliferative activity against human FEPD cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
10. | ALA4362326 | F | Antiproliferative activity against human H9 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
11. | ALA4362327 | F | Antiproliferative activity against human HH cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 14 | ALA4359870 | cell-based format | Scientific Literature | |
12. | ALA4362328 | F | Induction of cell cycle arrest in human FEPD cells assessed as accumulation at sub-G0 phase at 5 to 10 uM after 72 hrs by 7AAD staining based assay | Homo sapiens | 1 | ALA4359870 | cell-based format | Scientific Literature | |
13. | ALA4362329 | F | Induction of cell cycle arrest in human HUT78 cells assessed as accumulation at sub-G0 phase at 5 to 10 uM after 72 hrs by 7AAD staining based assay | Homo sapiens | 1 | ALA4359870 | cell-based format | Scientific Literature | |
14. | ALA4362330 | F | Induction of cell cycle arrest in human SUDHL8 cells assessed as accumulation at sub-G0 phase at 5 to 10 uM after 72 hrs by 7AAD staining based assay | Homo sapiens | 1 | ALA4359870 | cell-based format | Scientific Literature | |
15. | ALA4362331 | P | Aqueous solubility of compound at 1 mg after 24 hrs by LC-MS/MS analysis | 2 | ALA4359870 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA4362332 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 50 uM after 1 hr by UV/LC-MS analysis relative to control | Homo sapiens | 2 | ALA4359870 | microsome format | Scientific Literature | |
17. | ALA4362333 | A | Apparent permeability of compound at 500 uM after 5 hrs by UV/LC-MS analysis based GI-PAMPA assay | 2 | ALA4359870 | assay format | Scientific Literature | ||
18. | ALA4362334 | A | Membrane retention of compound at 500 uM after 5 hrs by UV/LC-MS analysis based GI-PAMPA assay relative to control | 2 | ALA4359870 | assay format | Scientific Literature |