# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4343116 | B | Inhibition of perforin (unknown origin) assessed as reduction in perforin-mediated cell lysis in human Jurkat T cells incubated for 30 mins by 51Cr release based gamma counting method | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
2. | ALA4343117 | B | Inhibition of perforin in human KHYG-1 cells pre-treated with compound for 20 mins assessed as reduction in KHYG-1 cells-mediated cell lysis of human K562 cells measured after 4 hrs by 51Cr release based gamma counting method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA4343118 | T | Toxicity in human KHYG-1 cells assessed as cell viability at 10 uM after 24 h by trypan blue exclusion assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
4. | ALA4343119 | B | Inhibition of perforin in human KHYG-1 cells pre-treated with compound for 20 mins assessed as reduction in KHYG-1 cells-mediated cell lysis of human K562 cells at 20 uM measured after 4 hrs by 51Cr release based gamma counting method | Homo sapiens | 9 | cell-based format | Scientific Literature |