#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4374580	Functional	DNA alkylating activity in human LNCAP cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
2.	ALA4374581	Functional	DNA alkylating activity in GCPII negative human PC3 cells exhibiting increased cathepsin B activity assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	assay format	Scientific Literature
3.	ALA4374582	Functional	DNA alkylating activity in human NCI-H292 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
4.	ALA4374583	Functional	DNA alkylating activity in human A549 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
5.	ALA4374584	Functional	DNA alkylating activity in human MCF7 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
6.	ALA4374585	Functional	DNA alkylating activity in human SKBR3 cells exhibiting increased cathepsin B activity and reduced GCPII expression assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
7.	ALA4374586	Functional	DNA alkylating activity in human SK-MEL-28 cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
8.	ALA4374587	Functional	DNA alkylating activity in human GCPII negative 16HBE14o cells deficient of cathepsin B activity assessed as reduction in cell viability incubated for 72 hrs by MTS assay	Homo sapiens	2	ALA4373672	assay format	Scientific Literature
9.	ALA4374589	Functional	DNA alkylating activity in GCPII negative human PC3 cells exhibiting increased cathepsin B activity assessed as reduction in cell viability incubated with GCPII binder 2-PMPA for 1 hr followed by incubation with compound for 48 hrs by MTS assay	Homo sapiens	2	ALA4373672	assay format	Scientific Literature
10.	ALA4374590	Functional	DNA alkylating activity in human LNCAP cells exhibiting increased cathepsin B activity and overexpressing GCPII assessed as reduction in cell viability incubated with GCPII binder 2-PMPA for 1 hr followed by incubation with compound for 48 hrs by MTS assay	Homo sapiens	2	ALA4373672	cell-based format	Scientific Literature
11.	ALA4374591	ADME	Stability in human plasma at 10 uM incubated for 120 mins by RP-HPLC analysis	Homo sapiens	1	ALA4373672	cell-free format	Scientific Literature
12.	ALA4374592	ADME	Stability of the compound in sodium acetate/EDTA containing reaction buffer assessed as human liver-derived Cathepsin B-mediated compound hydrolysis at 10 uM incubated for 120 mins by RP-HPLC analysis	Homo sapiens	1	ALA4373672	assay format	Scientific Literature