# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4385077 | F | Antiproliferative activity against human HL-7702 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
2. | ALA4385078 | B | Inhibition of TNF-alpha induced NF-kappaB activation in human A549 cells after 7 hrs by Bright-Glo luciferase reporter gene assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA4385079 | F | Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
4. | ALA4385080 | F | Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
5. | ALA4385081 | F | Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
6. | ALA4385082 | F | Antiproliferative activity against human A549 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
7. | ALA4385083 | F | Antiproliferative activity against human MG63 cells after 48 hrs by MTT assay | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
8. | ALA4385084 | B | Inhibition of IKKalpha/beta-mediated IkappaBalpha phosphorylation in human A549 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4385085 | B | Inhibition of TNF-alpha induced activation of NF-kappaB (unknown origin) assessed as reduction in DNA binding ability at 5 to 20 uM by cell based ELISA relative to TNF-alpha alone | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4385086 | B | Inhibition of IKKalpha/beta phosphorylation in human A549 cells up to 20 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4385087 | F | Reduction in IkappaBalpha level in human A549 cells up to 20 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4385088 | F | Growth inhibition of cisplatin sensitive human SKOV3 cells after 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA4385089 | F | Growth inhibition of cisplatin-resistant human SKOV3/DDP cells after 48 hrs by MTT assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
14. | ALA4385090 | F | Selectivity ratio of IC50 for cisplatin-resistant human SKOV3/DDP cells to IC50 for cisplatin sensitive human SKOV3 cells | Homo sapiens | 3 | assay format | Scientific Literature | ||
15. | ALA4385091 | F | Induction of apoptosis in human A549 cells after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4385092 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 1.28%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA4385093 | F | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 2.20%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA4385094 | F | Induction of apoptosis in human A549 cells assessed as necrotic apoptotic cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 0.520%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA4385095 | F | Induction of apoptosis in human A549 cells assessed as viable cells at 5 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 96.0%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA4385096 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 10 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry analysis (Rvb = 1.28%) | Homo sapiens | 1 | cell-based format | Scientific Literature |