# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4328864 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 15 mins | Homo sapiens | 33 | microsome format | Scientific Literature | ||
2. | ALA4328865 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining after 15 mins | Mus musculus | 33 | microsome format | Scientific Literature | ||
3. | ALA4328867 | B | Inhibition of Clostridium difficile toxin B transfected in CHO cells assessed as reduction in caspase 3/7 activation pre-incubated for 1 hr before TcdB addition by luminescence based assay | Clostridioides difficile | 35 | cell-based format | Scientific Literature | ||
4. | ALA4328868 | B | Inhibition of Clostridium difficile toxin A transfected in CHO cells assessed as reduction in caspase 3/7 activation pre-incubated for 1 hr before TcdA addition by luminescence based assay | Clostridioides difficile | 33 | cell-based format | Scientific Literature | ||
5. | ALA4328869 | B | Inhibition of C-terminal 6-His tagged recombinant Clostridium difficile toxin B glucosyltransferase domain assessed as reduction in UDP-glucose hydrolysis activity using UDP-glucose substrate and ADP Alexa633 tracer incubated for 3 hrs by fluorescence polarization assay | 33 | single protein format | Scientific Literature |