# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4374950 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked VIM-2 (27 to 266 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
2. | ALA4374951 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked NDM-1 (1 to 270 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
3. | ALA4374952 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked SFH1 (3 to 234 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
4. | ALA4374953 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked GOB-18 (1 to 290 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
5. | ALA4374954 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked KPC-2 (29 to 289 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
6. | ALA4374955 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked TEM-1 (24 to 286 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
7. | ALA4374956 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked AmpC (20 to 377 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
8. | ALA4374957 | Binding | Inhibition of bacterial N-terminal His-tagged TEV protease site linked OXA-48 (1 to 265 amino acids) expressed in Escherichia coli Transetta (DE3) preincubated for 10 mins followed by FC5 fluorescent substrate addition by fluorescence assay | Bacteria | 35 | ALA4373692 | assay format | Scientific Literature | |
9. | ALA4374960 | ADME | Inhibition of human C-terminal His/FLAG-tagged ACE-2 expressed in HEK293 cells at 100 uM preincubated for 10 mins followed by Mca-Ala-Pro-Lys(Dnp)-OH substrate addition by fluorescence assay relative to control | Homo sapiens | 24 | ALA4373692 | cell-based format | Scientific Literature |