# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4312562 | B | Inhibition of N-(3-Chlorophenyl-4,6-t2)-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine binding to his-tagged HIF-2alpha PAS-B domain (unknown origin) measured after 1 hr by scintillation proximity assay | Homo sapiens | 10 | ALA4311943 | single protein format | Scientific Literature | |
2. | ALA4312563 | B | Inhibition of HIF-2alpha (unknown origin) expressed in human 786-O cells measured after 24 hrs by one-glo luciferase reporter gene assay | Homo sapiens | 8 | ALA4311943 | cell-based format | Scientific Literature | |
3. | ALA4312565 | A | Substrate activity at recombinant human UGT2B17 expressed in baculovirus infected insect cell membranes assessed as enzyme-mediated glucuronidation by measuring Vmax per mg protein at 50 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA4311943 | assay format | Scientific Literature | |
4. | ALA4312566 | A | Substrate activity at recombinant human UGT2B17 expressed in baculovirus infected insect cell membranes assessed as enzyme-mediated glucuronidation by measuring Km at 50 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA4311943 | assay format | Scientific Literature | |
5. | ALA4312567 | A | Substrate activity at UGT2B17 in human intestinal microsomes assessed as enzyme-mediated glucuronidation by measuring Vmax per mg protein at 2 to 1000 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA4311943 | microsome format | Scientific Literature | |
6. | ALA4312568 | A | Substrate activity at UGT2B17 in human intestinal microsomes assessed as enzyme-mediated glucuronidation by measuring Km at 2 to 1000 uM preincubated for 5 mins followed by UDPGA addition and measured after 60 mins by LC-MS/MS analysis | Homo sapiens | 7 | ALA4311943 | microsome format | Scientific Literature |