# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4434000 | F | Effect on IL-6 production in TLR2-/- mouse BMDM cells at 0.1 to 1 uM incubated for 24 hrs by ELISA | Mus musculus | 7 | ALA4433228 | cell-based format | Scientific Literature | |
2. | ALA4434016 | B | Agonist activity at TLR2/6 in PMA-differentiated human THP-1 cells assessed as induction of IL-6 production at 2.5 uM incubated for 24 hrs after preincubation with anti-hTLR1-IGA for 2 hrs by ELISA | Homo sapiens | 1 | ALA4433228 | cell-based format | Scientific Literature | |
3. | ALA4434017 | B | Agonist activity at TLR2/1 in mouse BV2 cells assessed as induction of IL-6 production at 2 uM incubated for 24 hrs in presence of TLR2/1 inhibitor CU-CPT22 by ELISA | Mus musculus | 1 | ALA4433228 | cell-based format | Scientific Literature | |
4. | ALA4434019 | A | Cytotoxicity against mouse BV2 cells assessed as cell viability up to 5 uM incubated for 24 hrs by CCK-8 assay | Mus musculus | 4 | ALA4433228 | cell-based format | Scientific Literature | |
5. | ALA4434020 | B | Agonist activity at TLR2 in mouse BV2 cells assessed as increase in IL-6 secretion at 2 uM incubated for 24 hrs by ELISA | Mus musculus | 4 | ALA4433228 | cell-based format | Scientific Literature |