# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4364068 | B | Inhibition of human recombinant MBP-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substrate addition and measured after every 20 mins for 4 hrs by fluorescence based assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA4364069 | B | Inhibition of rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substrate addition and measured after every 20 mins for 4 hrs by fluorescence based assay | Rattus norvegicus | 32 | cell-based format | Scientific Literature | ||
3. | ALA4364070 | B | Inhibition of human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells using AHMMCE as substrate preincubated with enzyme for 15 mins followed by substrate addition and measured after every 15 mins for 3 hrs by fluorescence based assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
4. | ALA4364080 | A | Stability in human liver microsomes assessed as half life | Homo sapiens | 21 | microsome format | Scientific Literature | ||
5. | ALA4364081 | A | Stability in rat liver microsomes assessed as half life | Rattus norvegicus | 21 | microsome format | Scientific Literature | ||
6. | ALA4364082 | A | Stability in mouse liver microsomes assessed as half life | Mus musculus | 21 | microsome format | Scientific Literature | ||
7. | ALA4364083 | A | Stability in human plasma assessed as half life | Homo sapiens | 21 | cell-free format | Scientific Literature | ||
8. | ALA4364084 | A | Stability in rat plasma assessed as half life | Rattus norvegicus | 21 | cell-free format | Scientific Literature | ||
9. | ALA4364085 | A | Stability in mouse plasma assessed as half life | Mus musculus | 21 | cell-free format | Scientific Literature | ||
10. | ALA4364086 | A | Stability in human gastric fluid assessed as half life | Homo sapiens | 21 | tissue-based format | Scientific Literature | ||
11. | ALA4364087 | A | Stability in rat gastric fluid assessed as half life | Rattus norvegicus | 21 | tissue-based format | Scientific Literature | ||
12. | ALA4364088 | A | Stability in mouse gastric fluid assessed as half life | Mus musculus | 21 | tissue-based format | Scientific Literature | ||
13. | ALA4364095 | B | Selectivity ratio of IC50 for human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells to IC50 for human recombinant MBP-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
14. | ALA4364096 | B | Selectivity ratio of IC50 for human full length ABHD6 expressed in Escherichia coli cells to IC50 for human recombinant MBP-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | Homo sapiens | 34 | cell-based format | Scientific Literature | ||
15. | ALA4364097 | B | Displacement of [3H]CP55940 from CB1 receptor in rat brain by competition-equilibrium binding analysis | Rattus norvegicus | 40 | tissue-based format | Scientific Literature | ||
16. | ALA4364098 | B | Displacement of [3H]CP55940 from CB2 receptor in rat brain by competition-equilibrium binding analysis | Rattus norvegicus | 40 | tissue-based format | Scientific Literature | ||
17. | ALA4364099 | B | Displacement of [3H]CP55940 from mouse CB2 receptor expressed in HEK293 cells by competition-equilibrium binding analysis | Mus musculus | 40 | cell-based format | Scientific Literature | ||
18. | ALA4364100 | B | Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cells by competition-equilibrium binding analysis | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
19. | ALA4364103 | B | Selectivity ratio of IC50 for human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells to IC50 for rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | 34 | cell-based format | Scientific Literature | |||
20. | ALA4364104 | B | Selectivity ratio of IC50 for human full length ABHD6 expressed in Escherichia coli cells to IC50 for rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells by fluorescence based assay | 34 | cell-based format | Scientific Literature |