| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4374299 | B | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as reduction in IKZF1 degradation at 0.001 to 0.01 uM after 16 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4374301 | F | Antiproliferative activity against human MM1S cells at 1 nM to 10 uM after 4 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4374303 | B | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as IKZF1 degradation by measuring IKZF1/tubulin ratio at 1 uM after 16 hrs by Western blot analysis relative to tubulin | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA4374304 | B | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as IKZF1 degradation by measuring IKZF1/tubulin ratio at 0.1 uM after 16 hrs by Western blot analysis relative to tubulin | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA4374305 | B | Protac activity at CRBN/ IKZF1 in human MM1S cells assessed as CRBN degradation at 100 nM to 1 uM after 16 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |
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