# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4373194 | B | Inhibition of recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | ALA4371074 | assay format | Scientific Literature | |
2. | ALA4373195 | B | Inhibition of recombinant human C-terminal His10-tagged hepsin catalytic domain preincubated for 30 mins followed by Boc-QAR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | ALA4371074 | single protein format | Scientific Literature | |
3. | ALA4373196 | B | Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by fluorescence assay | Homo sapiens | 21 | ALA4371074 | single protein format | Scientific Literature | |
4. | ALA4373198 | B | Selectivity ratio of Ki(app) for recombinant human N-terminal His6-tagged matriptase catalytic domain expressed in Escherichia coli to Ki(app) for recombinant human C-terminal His10-tagged hepsin catalytic domain | Homo sapiens | 8 | ALA4371074 | assay format | Scientific Literature | |
5. | ALA4374436 | B | Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by chromogenic assay | Homo sapiens | 18 | ALA4373666 | single protein format | Scientific Literature | |
6. | ALA4374437 | B | Inhibition of recombinant factor Xa (unknown origin) using Bz-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by chromogenic assay | Homo sapiens | 18 | ALA4373666 | single protein format | Scientific Literature | |
7. | ALA4374438 | B | Inhibition of recombinant HGFA serine protease domain (unknown origin) using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay | Homo sapiens | 20 | ALA4373666 | single protein format | Scientific Literature | |
8. | ALA4374439 | B | Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay | Homo sapiens | 20 | ALA4373666 | cell-based format | Scientific Literature | |
9. | ALA4374440 | B | Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay | Homo sapiens | 20 | ALA4373666 | assay format | Scientific Literature |