# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418863 | B | Inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 71 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4418864 | B | Inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
3. | ALA4418865 | B | Inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
4. | ALA4418866 | B | Inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
5. | ALA4418872 | B | Selectivity index, ratio of IC50 for inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells to IC50 for inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4418873 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli to IC50 for inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli | Homo sapiens | 18 | assay format | Patent Bioactivity Data | ||
7. | ALA4418874 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli to IC50 for inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli | Homo sapiens | 4 | assay format | Patent Bioactivity Data |